Principal Project Manager, Cell and Tissue Genomics (CTG)

Roche • South San Francisco, CA

6d • Remote

About The Position

At CTG we generate data at scale using cutting edge single cell technologies. We are seeking a Principal Project Manager who remains composed in the face of large-scale profiling efforts to generate foundational data and possesses the meticulous coordination required to manage the many moving parts of grand-scale scientific initiatives. As a Principal Project Manager within the Cell and Tissue Genomics (CTG) department, you will serve as the essential bridge between high-level scientific strategy and large-scale laboratory execution. Your role will be to help enable these large scale data generation projects and to track their progress. Study Design & Planning: Partner with Principal Investigators (PIs) and FDFM leadership to translate ambitious research goals into actionable detailed project plans with clear deliverables and, detailed timelines Pipeline Orchestration: Manage the end-to-end projects, ensuring critical milestones are achieved during the pilot,scale-up and validation phases. Cross-Functional Leadership: Act as the "connective tissue" between bench scientists,computational/AI scientists, regulatory affairs, and external stakeholders to ensure organizational alignment. Risk Mitigation: Proactively identify operational risks—and develop robust contingency plans. Protocol & Regulatory Compliance: Manage the oversight, submission and renewal of internal oversight protocols. Financial Stewardship: Monitor research expenditures and personnel against funding to ensure all spending remains aligned with approved budgetary line items and institutional fiscal cycles. Who You Are Ph.D. in a Biological Science (Molecular Biology, Genetics, Immunology, Oncology or a related field) is required. Project Management : 5+ years of experience overseeing complex projects involving clinical tissue samples, specifically focused on single-cell assays and spatial profiling. Proven ability to harmonize workflows across multidisciplinary teams, bridging the gap between wet-lab operations and computational analysis. Bench Expertise: Minimum of 4 years of hands-on wet-lab experience. You must intimately understand the "rhythm" of the lab to manage its outputs effectively. Regulatory Knowledge: Deep understanding of EHS (Environmental Health and Safety) standards, BSL-2/3 laboratory requirements and IRBs. Software Proficiency: Expert-level command of project management tools (e.g., Miro, Trello, or MS Project) Exceptional organizational skills with a proven track record of managing high-volume, high-complexity large scale profiling efforts. Strong interpersonal skills with the ability to influence cross-functional teams without direct authority.

Requirements

• Ph.D. in a Biological Science (Molecular Biology, Genetics, Immunology, Oncology or a related field) is required.
• 5+ years of experience overseeing complex projects involving clinical tissue samples, specifically focused on single-cell assays and spatial profiling.
• Proven ability to harmonize workflows across multidisciplinary teams, bridging the gap between wet-lab operations and computational analysis.
• Minimum of 4 years of hands-on wet-lab experience. You must intimately understand the "rhythm" of the lab to manage its outputs effectively.
• Deep understanding of EHS (Environmental Health and Safety) standards, BSL-2/3 laboratory requirements and IRBs.
• Expert-level command of project management tools (e.g., Miro, Trello, or MS Project)
• Exceptional organizational skills with a proven track record of managing high-volume, high-complexity large scale profiling efforts.
• Strong interpersonal skills with the ability to influence cross-functional teams without direct authority.

Nice To Haves

• PMP (Project Management Professional) or CAPM certification is highly preferred.

Responsibilities

• Partner with Principal Investigators (PIs) and FDFM leadership to translate ambitious research goals into actionable detailed project plans with clear deliverables and, detailed timelines
• Manage the end-to-end projects, ensuring critical milestones are achieved during the pilot,scale-up and validation phases.
• Act as the "connective tissue" between bench scientists,computational/AI scientists, regulatory affairs, and external stakeholders to ensure organizational alignment.
• Proactively identify operational risks—and develop robust contingency plans.
• Manage the oversight, submission and renewal of internal oversight protocols.
• Monitor research expenditures and personnel against funding to ensure all spending remains aligned with approved budgetary line items and institutional fiscal cycles.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees