Principal Pharmaceutical Scientist

Boston Scientific•Osseo, MN

5d•$99,100 - $188,300•Onsite

About The Position

This Principal Pharmaceutical Scientist is responsible for design and optimization formulation of drug delivery systems to support combination product development, preclinical and clinical studies. This position is also responsible for characterizing physicochemical properties such as physical form, solubility, stability, and interaction of drug molecules with excipients. This includes experimental planning, design, data analysis and interpretation. At Boston Scientific, our products and technologies are used to diagnose or treat a wide range of medical conditions. We continue to innovate in key areas and are extending our innovations into new geographies and high-growth adjacency markets. As part of R D team, we design, develop, and produce technologies for diagnosing and treating coronary artery disease and other cardiovascular disorders. Medical Conditions we provide solutions that encompass Coronary Artery Disease, Peripheral Artery Disease, Heart Failure, and other Cardiovascular Diseases. We are able to provide a number of solutions to patients that include: Drug-Eluting Stents, Bare-Metal Stents, Catheters, Balloons, Guide Wires, Coronary Atherectomy and Coronary Intravascular Ultrasound. BSC has robust product portfolio and pipeline and will continue to make investment in Interventional treatments to improve the quality of patient's life.

Requirements

PhD in Pharmaceutical Sciences, Physical/Polymer Chemistry, Material Science, Chemical Engineering, Biomedical Engineering, or related technical field.
5 to 7 years of Medial Device, polymer materials or Pharmaceutical industry experience under a research and development environment.
Strong hands-on capability and deep understanding of pharmaceutics and physical chemistry is a must.

Nice To Haves

Understanding and experience in translation pre-clinical model development
Knowledge of major analytical techniques such as HPLC, GC, LC/MS, GC/MS, and NMR are desirable.
Strong interpersonal and communication skills
Good technical writing skills
Substantial knowledge in assay method development and validation and familiarity with drug release and stability testing are desirable.
Good understanding of controlled drug delivery systems and ICH guidance are highly desirable
Experience in practical lab-based Pharmacokinetics/Pharmacodynamics data analysis
Must have critical thinking, curiosity and problem-solving skills

Responsibilities

Selects techniques to solve complex problems and makes sound design recommendations.
Solid understanding on controlled drug release mechanism.
Drug release and stability testing at internal and external laboratories
Write CMC sections to support IDE and PMA submissions for combination products
Participate in cross-functional product development teams and provide technical leadership to formulation development, test methods, sterilization process selection, packaging specification requirements, clinical manufacturing, quality assurance, analytical R D, and regulatory affairs
Consistently generates innovative and unique solutions to market needs and submits idea disclosures. Work is expected to result in the development of new or refined products, processes, or equipment.
The selected candidate must have an ability to collaborate effectively with other scientists in a multidisciplinary team environment and possess excellent verbal and written communication skills.
Ability to research literature and develop clinical understanding with technical credibility to develop a strategy for regulatory submission.
Demonstrated ability to provide technical leadership on a large-scale development program.
Providing technical direction to technicians/entry-level engineers, mentor junior level engineer
Actively collaborating with process development, quality, manufacturing, regulatory, clinical, and marketing on complex projects to ensure project success.