Postdoctoral Scientist – All Levels

Texas Biomedical Research Institute • San Antonio, TX

8h • Onsite

About The Position

The Speranza Lab at Texas Biomedical Research Institute (Texas Biomed) is seeking a highly motivated Postdoctoral Fellow to study host immune responses to emerging RNA viruses. Our research focuses on understanding how the immune system responds during the earliest stages of infection and identifying mechanisms that shape disease outcomes.

This project will leverage systems immunology approaches, including spatial and cellular profiling technologies, to dissect early host responses to emerging RNA viruses in vivo. The work integrates advanced molecular profiling, high-content imaging, and computational analysis to understand how immune responses are organized across tissues and cell types during infection.

Research will involve work in BSL-3 and BSL-4 laboratory environments, providing a unique opportunity to study high-consequence viral pathogens in a collaborative and well-supported high-containment research setting.

The successful candidate will lead and contribute to projects aimed at characterizing early immune responses to emerging RNA viruses using cutting-edge systems biology approaches.

Requirements

• PhD in immunology, virology, computational biology, or a related biomedical field required
• Demonstrated experience analyzing single-cell sequencing data
• Experience with high-content imaging or related quantitative imaging approaches
• Excellent written and verbal communication skills

Nice To Haves

• Prior experience working in BSL-3 or BSL-4 laboratory environments
• Experience working with small animal models of infectious disease
• Background in systems immunology, spatial transcriptomics, or high-dimensional immune profiling

Responsibilities

• Designing and conducting experiments to investigate host immune responses to viral infection in vivo
• Analyzing and interpreting single-cell sequencing datasets and other high-dimensional profiling data
• Utilizing high-content imaging and spatial profiling technologies
• Working collaboratively within a multidisciplinary team of virologists, immunologists, and computational scientists
• Contributing to manuscript preparation, grant development, and presentation of research findings at scientific meetings

Benefits

• Recognized as one of the San Antonio Business Journal’s Best Places to Work in 2025.
• Awarded the 2024 Healthy Workplace Platinum Recognition by the San Antonio Business Group on Health (SABGH).
• Employee-centered culture focused on open communication, job empowerment, and trust.
• Comprehensive health, dental, vision, and life insurance plans for you and your family (including your pets!).
• Competitive employer-funded retirement plan with 6% contributions starting on day one, increasing with years of service.
• Generous paid time off, including 14 paid holidays and a paid Winter Recess (last week of December until New Year’s).
• On-site medical clinic, wellness incentives, and paid prescription drug resources to support your health.
• On-site gym and wellness programs to help you stay active.
• Flexible work arrangements designed to support work-life balance.
• We offer a relaxed dress code so you can feel comfortable and be yourself at work.
• Dynamic learning environment with professional development, mentorship, tuition reimbursement, and leadership programs to help you grow.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree