Postdoctoral Scholar - Research Associate

University of Southern CaliforniaLos Angeles, CA
9dOnsite

About The Position

USC’s Keck School of Medicine, Department of Medicine, is seeking a highly motivated Postdoctoral Research Associate to join the Division of Gastrointestinal and Liver Diseases under the supervision of the principal investigator (PI), Dr. Lily Dara. This NIH-funded post-doctoral position is available to study immune mediate liver injury and hepatotoxicity pathways that control the innate and adaptive immune responses in the liver in the context of drug-induced liver injury. This position will be focused on defining molecular and cellular mechanisms control immune responses and cell death pathways in the liver using animal models, in-vitro models, NAMs, and importantly translational approaches using patient biospecimens. The applicant must be able and willing to work with transgenic animal models, as well as human biospecimens. This exciting study integrates cutting edge molecular technologies with traditional cell & molecular biology-based approaches. Please refer to our recent publications for further information: https://pubmed.ncbi.nlm.nih.gov/?term=dara%2C+lily&sort=date We are seeking highly motivated and collaborative individuals capable of independent reasoning and excited about learning new technologies and translational approaches related to hepatotoxicity. The candidates should have excellent writing and communication skills and be familiar with techniques such as multi color flow cytometry, cell isolation, tissue culture, ELISA, RT-PCR, animal handling and familiar with molecular biology. There will be on the job training for many of the advanced immunology techniques and you will leave this position primed for an academic career or a drug safety position in pharma and biotechnology companies. This job is open only for recent graduate applicants with PhD or applicants that expect to graduate from PhD program soon. Bonus, if there is a background in liver disease, toxicology, or pharmaceutical sciences. The laboratory is located in the Hoffman Medical Research Building. Animal rooms and core state- of the art research facilities are on campus equipped with genomics cores for single cell studies and immunology facilities with flow cytometry analyzer, FACs and magnetic sorters, confocal microscopy, etc. Both of USC’s primary campuses are located in the heart of Los Angeles, with easy access to LA Live, the city’s new sports and entertainment center, and downtown LA. On campus you will find a vibrant aca demic, athletic and artistic culture that involves students, staff and faculty from across the university. Specific job accountabilities will be: Planning, generating scientific hypotheses, and conducting highly technical and complex research projects independently and in consultation with the PI. Coordinating timelines to ensure completion of deliverables linked to progress reports and RPPR submissions. Identifying, researching, compiling, and evaluating data sources, background information, and/or technology related to the area of specialization. Analyzing and evaluating research data using computers and providing interpretations requiring significant knowledge of a specialized area of research. Searching literature, utilizing all available resources including electronic, regarding new methodology and designing experiments accordingly. Contributing to the development of research documentation for publication and/or prepares technical reports and/or records to support regulatory and NIH reporting requirements. Operating and maintaining sophistocated laboratory/scientfic equipment. Working with transgenic animal cell lines and tumor models.

Requirements

  • Excellent writing and communication skills
  • Familiar with techniques such as multi color flow cytometry, cell isolation, tissue culture, ELISA, RT-PCR, animal handling and familiar with molecular biology.
  • Recent graduate applicants with PhD or applicants that expect to graduate from PhD program soon.

Nice To Haves

  • Background in liver disease, toxicology, or pharmaceutical sciences.

Responsibilities

  • Planning, generating scientific hypotheses, and conducting highly technical and complex research projects independently and in consultation with the PI.
  • Coordinating timelines to ensure completion of deliverables linked to progress reports and RPPR submissions.
  • Identifying, researching, compiling, and evaluating data sources, background information, and/or technology related to the area of specialization.
  • Analyzing and evaluating research data using computers and providing interpretations requiring significant knowledge of a specialized area of research.
  • Searching literature, utilizing all available resources including electronic, regarding new methodology and designing experiments accordingly.
  • Contributing to the development of research documentation for publication and/or prepares technical reports and/or records to support regulatory and NIH reporting requirements.
  • Operating and maintaining sophistocated laboratory/scientfic equipment.
  • Working with transgenic animal cell lines and tumor models.

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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