This position is with the Division of Endocrinology Metabolism and Lipid Research at WashU. The laboratory of Dr. Carlos Bernal-Mizrachi, Philip E. and Carolyn E. Cryer Professor of Medicine and Chief of Medicine at the St. Louis VA Medical Center, invites applications for a full-time Postdoctoral Research Fellow. The laboratory is engaged in NIH-funded basic and translational research focused on the mechanisms by which prenatal vitamin D deficiency and hyperglycemia programs cardiovascular and metabolic disease across the lifespan. The laboratory has decades of experience in basic and translational research evaluating the mechanisms by which vitamin D and acute hyperglycemia modulates innate immune cells and the inflammatory milieu that contributes to the development of insulin resistance, hypertension and cardiovascular disease. Ongoing work explores the following interconnected areas: Epigenetic programming of fetal liver HSCs by in utero vitamin D deficiency and the transplantability of hypertension and insulin resistance. Mechanistic dissection of the vitamin induced immune program in vascular and metabolic diseases. The effect of acute hyperglycemia and immune cell metabolism and function. Human translational validation using the VDAART randomized clinical trial cohort (prenatal vitamin D supplementation, childhood cardiometabolic outcomes, methylation arrays). Developmental programming of insulin resistance, adiposity, and metabolic disease. This is an exceptional opportunity for a highly motivated scientist to work at the interface of epigenetics, immunity, vascular physiology, and human translational research, within a collaborative and highly productive academic environment. Job Description Primary Duties & Responsibilities: Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.
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Job Type
Full-time
Career Level
Intern
Education Level
Ph.D. or professional degree