Postdoctoral Fellow-MSH-32074-058
About The Position
Metabolism plays a critical role in cellular, tissue, and organismal homeostasis by fulfilling the energetic and biosynthetic demands of life. Despite this, we still do not know or understand all the metabolic transporters and enzymes involved in shaping metabolism. The Kenny Lab uses systems biology approaches such as CRISPR-based genetic screens, metabolomics, organellar immunocapture, and human multi-omic datasets to uncover novel components of metabolic pathways. These insights, in turn, are used to understand metabolism at a fundamental level and discover their contribution to human disease pathogenesis. The postdoctoral fellow will use such approaches to expand upon ongoing projects in the lab and branch into new aspects of metabolism. This research project will provide a postdoctoral fellow with exceptional training which will prepare them to start their own independent research group or pursue other career goals. Scientifically, this project will uncover fundamental aspects of mammalian metabolism thereby uncovering potential novel therapeutics that can be modulated through diet or pharmacology to treat human disease.
Requirements
- PhD in Biomedical Sciences focusing on biochemistry, molecular and cellular biology, metabolism, physiology, or a related field
- Experience working with mouse models and mammalian cell culture.
- Experience with molecular and cellular biology techniques.
Nice To Haves
- Experience with bioinformatics and working knowledge of scripting languages (i.e. R) are not required but considered an asset.
Responsibilities
- Design and perform experiments focused on cellular and organismal metabolism
- Learn metabolic techniques including LC/MS-based metabolomics and isotope tracing/flux experiments using in vitro and in vivo model systems.
- Develop genetically engineered mouse models to dissect the influence of specific metabolites on organismal physiology and mouse models of disease
- Mentor and train research trainees
- Prepare work for presentation, publication, and grants
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
