Postdoctoral Fellow in Pharmacokinetics Laboratory

CommonSpirit Health • Phoenix, AZ

4h

About The Position

The Ivy Brain Tumor Center at Barrow Neurological Institute is a non-conventional, non-profit program offering state-of-the-art clinical trials for patients with the most aggressive form of brain cancer. It is home to the largest collection of Phase 0 trials for brain tumors in the world. Our multidisciplinary team of brain tumor specialists and scientists are accelerating drug discovery and precision medicine in neuro-oncology to identify the most promising first-in-class therapies for brain tumor patients.
Job Description: To develop brain targeting therapeutics via rational design and neuro-pharmacokinetic assessment through preclinical and clinical studies.
We are looking for an individual to join the Pharmacokinetics (PK) Lab as a postdoctoral associate. The candidate s hould have a strong background in chemical/pharmaceutical sciences with a reasonable working knowledge of translational research. Candidates who have experience in LC-MS/MS-based method development/validation and can demonstrate competency in pharmacokinetic data analysis will be preferred. The candidate should be able to work well in highly collaborative environment and have excellent communication skills. Potential areas of application include bioanalysis, medicinal chemistry, drug development, drug PK, organic synthesis, method validation, biomarker analysis, and PK modeling. The candidate is encouraged to apply for internal and external grants.

Requirements

• Ph.D., post-baccalaureate M.D. or D.Sc. degree or equivalent in a relevant field of endeavor and Laboratory or clinical research at the post-baccalaureate level with an interest in a faculty member's line of study, upon hire
• Recommendation letters
• Ph.D. or equivalent degree (MD, DVM, PharmD, etc.) in Pharmaceutical Sciences, Chemistry, Biochemistry, Medical Sciences or in related disciplines.

Nice To Haves

• Research experience in organic synthesis, bioanalysis, medicinal or pharmaceutical chemistry areas.
• Experience with UHPLC or LCMS-based assay development.
• Experience with rational drug design and development, physicochemical characterization.
• Experience in biomedical research (cellular techniques and animal handling).
• Experience with maintenance and troubleshooting of LC and MS systems.
• Good organizational and analytical skills.
• Ability to work independently and cohesively as part of a team.

Responsibilities

• Development, validation and implementation of analytical methods for various drugs, drug candidates, metabolites, and biomarkers employing UHPLC and LC-MS/MS techniques.
• Performing pharmacokinetic data analyses.
• Manuscript preparation and publishing.
• Supervision and training of laboratory supporting research staff.
• Preparation and delivery of research presentations at local meetings, national and international conferences.
• General operation, maintenance, and troubleshooting of laboratory equipment, including UHPLC and LC- MS/MS instruments.
• Preparation and maintenance of required laboratory safety documentation and adherence to the guidelines and regulations in compliance with CAP/CLIA and HIPAA rules.

What This Job Offers

• Career Level: Entry Level
• Education Level: Ph.D. or professional degree