Postdoctoral Fellow-MSH-30020-170

Mount Sinai Health SystemNew York, NY
Onsite

About The Position

The Blanchard Laboratory is seeking highly skilled, creative, and motivated scientists to join our team studying how genetic and environmental factors shape the human brain’s vulnerability to neurodegenerative disease. Our research focuses on uncovering the cellular and molecular mechanisms underlying Alzheimer’s disease and related neurodegenerative disorders, with the goal of identifying new therapeutic strategies. To accomplish this, the lab develops and applies advanced human iPSC-based brain models, including multicellular organoid and assembloid systems that recapitulate key aspects of human brain biology. These platforms are integrated with genomic, computational, and systems-level approaches to understand how genetic risk factors and environmental exposures drive disease processes. Projects in the laboratory span multiple areas of neurodegeneration research, including: Genetic risk mechanisms in Alzheimer’s disease (e.g., APOE biology) Neurovascular and glial contributions to neurodegeneration Lipid metabolism and metabolic stress in the aging brain Human brain organoid and assembloid engineering Multi-omics analysis of human brain tissue and disease models Our experimental platforms combine human iPSC models, post-mortem human brain analysis, and mouse models, enabling mechanistic discoveries that directly inform translational research.

Requirements

  • PhD
  • 4-5 years Experience

Responsibilities

  • Genetic risk mechanisms in Alzheimer’s disease (e.g., APOE biology)
  • Neurovascular and glial contributions to neurodegeneration
  • Lipid metabolism and metabolic stress in the aging brain
  • Human brain organoid and assembloid engineering
  • Multi-omics analysis of human brain tissue and disease models

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What This Job Offers

Job Type

Full-time

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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