Postdoctoral Fellow – Molecular Neurogenetics
About The Position
A little about us: The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention. We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD. Job Summary: We are seeking an enthusiastic and self-motivated postdoctoral associate with experience in molecular cell biology to join our interdisciplinary research team at the Lieber Institute for Brain Development, located on the Johns Hopkins medical campus in Baltimore, Maryland (https://www.libd.org/functional-genomics/). This position is open to scientists seeking a position within a translational research setting with a focus on human stem cell projects using induced pluripotent stem cell (iPSC)-derived trophoblasts and neuronal cells. The successful applicant will work closely in collaboration with a team of wet bench and computational scientists to investigate the consequences of compromised pregnancy on neurodevelopment with the goal of deciphering in utero mechanisms underlying neurodevelopmental and psychiatric disorders. Responsibilities will include experimental design, executing protocols independently, analyzing data, as well as communicating scientific findings through presentations and publications.
Requirements
- PhD in cell and molecular biology, neuroscience, or a closely related field
- Cellular and molecular biology and/or neuroscience experience
- Bench experience with culturing stem cells, molecular profiling assays or transcriptomic analysis would be beneficial
- Flexible work schedule (this position will require work for extended hours and on weekends and holidays, depending on the cell culture schedule)
- Exceptional wet lab skills
- Computational experience or familiarity with computing in R or Python is a plus.
- Strong motivation to learn new methods and perform work efficiently and carefully are essential.
- Strong troubleshooting skills and ability to independently resolve technical challenges
- Excellent communication and collaborative skills, with ability to work effectively in a team-based environment
Nice To Haves
- Human PSC culture and trophoblast and/or neuronal differentiation
- Programming in R or Python
- Proteomics or metabolomics analysis
- Single-cell or spatially-resolved transcriptomic analysis
- Experience leading manuscript preparation
- Human placental biology
- Human neurodevelopmental biology
Responsibilities
- Culturing human iPSC and derivative cell lines
- Immunocytochemistry, single-molecule FISH, ELISA, western blot, RT-qPCR
- Sample preparation for proteomics, metabolomics, single-cell transcriptomics, and spatially-resolved transcriptomic analyses
- Maintain detailed experimental records and ensure reproducibility of protocols
- Other duties as assigned
Benefits
- The Lieber Institute for Brain Development offers a competitive, comprehensive benefits package to help us attract and retain the best talent.
- Please visit https://www.libd.org/careers/benefits/ for more information.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
