About The Position

Van Andel Institute (VAI), a world-class biomedical research institute, located in Grand Rapids, Michigan, is dedicated to improving human health. We are pioneers in the fight against cancer, Parkinson's, and other diseases. We are committed to inspiring the next generation of scientists and educators. A postdoctoral position is available in the laboratory of Dr. Maulik Patel in the Department of Metabolism and Nutritional Programming at the Van Andel Institute (VAI). The Patel Lab studies fundamental aspects of mitochondrial biology using Caenorhabditis elegans as a model system. Our research focuses on understanding mitochondrial DNA (mtDNA) biology, including mechanisms regulating mtDNA copy number, maintenance, and inheritance. The postdoctoral researcher will investigate key questions in mitochondrial genome regulation and function. Projects in the lab combine genetics, molecular biology, biochemistry, and imaging approaches in C. elegans to uncover how mtDNA copy number is controlled and how mitochondrial function is maintained across development and physiological states. In particular, there is strong interest in reconstituting aspects of mtDNA regulation in vitro using purified components and developing biochemical assays to study protein–DNA interactions relevant to mitochondrial genome maintenance. Candidates will have the opportunity to develop independent research directions aligned with the lab’s broader goals. The successful candidate will be trained in both established and cutting-edge technologies and will work in a highly collaborative and interdisciplinary environment. The Van Andel Institute is a leading independent nonprofit biomedical research and education organization, home to a vibrant scientific community engaged in fundamental and translational research.

Requirements

  • Ph.D. in cell biology, genetics, molecular biology, biochemistry, or a related field.
  • Experience in one or more of the following areas: mitochondrial biology, genetics, C. elegans research, molecular biology, cell biology, or biochemistry.
  • Demonstrated ability to independently design and execute research projects.
  • Strong record of scientific productivity (e.g., first-author publications).

Nice To Haves

  • Experience with protein purification, biochemical reconstitution, and/or in vitro assays (e.g., protein–DNA interactions) is highly desirable.

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

Number of Employees

251-500 employees

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