Postdoctoral Associate
About The Position
The mission of our team is to translate novel drug-delivery technologies to treat children with brain tumors. The brain has a natural barrier that prevents toxins and other agents from reaching the brain. This same barrier also limits the access of systemic treatments, including chemotherapy, targeted therapy, and immunotherapy, from reaching the tumor. We are interested in exploring the usage of focused ultrasound (FUS) and convection-enhanced delivery (CED). Using targeted ultrasound, or FUS, with microbubbles, the blood-brain barrier (BBB) can temporarily and reversibly open to allow for enhanced drug delivery to fight brain tumors. In addition, we are also exploring the use of direct catheter delivery of drugs to brain tumors using CED. We are focusing on identifying novel methods to treat Pediatric Brain tumors using new Drug Delivery Approaches and novel agents. Our goal is to translate into Novel Clinical Trials for children suffering from brain tumors. We are seeking candidates with experience in cell culture work, molecular biology, and preclinical tumor models. Successful candidates will be highly motivated individuals with a doctoral degree in Neurology, Oncology, or Immunology, have excellent communication skills, be able to function independently, and participate as part of a dynamic team. The successful candidate will be involved in generating preclinical data that will lead to the design a number of novel clinical studies in children with high-grade gliomas and other brain tumors. Work Location: Fralin Biomedical Research Institute at VTC, Roanoke, VA https://fbri.vtc.vt.edu/
Requirements
- PhD in Oncology, Neuroscience, Immunology, or appropriate related disciplines. PhD must be awarded no more than four years prior to the effective date of appointment with a minimum of one year eligibility remaining.
- Creative, independent, and highly motivated, with good communication skills.
- Demonstrated publication of research findings in peer-reviewed journals.
- Experience in cell biology, molecular biology, and preclinical animal models.
Nice To Haves
- Experience with flow cytometry.
- Experience with RNA sequencing and analysis.
- Experience with gene-editing techniques in cells or animals.
Responsibilities
- Generating preclinical data that will lead to the design a number of novel clinical studies in children with high-grade gliomas and other brain tumors.
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What This Job Offers
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees
