Postdoctoral Associate (Multiple Positions)

Rutgers UniversityPiscataway, NJ
15h

About The Position

Rutgers, The State University of New Jersey, is seeking a Postdoctoral Associate for the department of Biochemistry and Molecular Biology at the Robert Wood Johnson Medical School. The Mickolajczyk laboratory is recruiting Postdoctoral Associates to engage in ongoing research projects relative to studying the mechanisms of pre-ribosome maturation by motor proteins and regulation and substrate-targeting by ATPase enzymes in ribosome biogenesis. The main project involves studying the mechanisms of pre-ribosome maturation by motor proteins, an essential process for generating new ribosomes that are properly folded and competent for protein translation. Force spectroscopy (optical and magnetic tweezers), single-molecule fluorescence, and bulk biochemical methods will be used to investigate how these motor proteins convert the energy from ATP hydrolysis into mechanical work in order to promote pre-ribosomal folding. The assays developed will be used to benchmark wildtype versus disease-derived mutants of motor proteins to investigate the molecular bases of ribosomopathies and other ribosome-dependent diseases. The Post Doctoral Associate will also have the opportunity to participate in ongoing collaborative projects, as well as to spearhead new projects within the lab. New Jersey’s academic health center, Rutgers Biomedical and Health Sciences ( RBHS ) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University–New Brunswick and collaborating university wide, RBHS includes eight schools, a behavioral health network, and five centers and institutes that focus on cancer treatment and research, neuroscience, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research. Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers. Our clinical and academic facilities are located throughout the state—at Rutgers University–New Brunswick, including Piscataway; and at locations in Newark, Scotch Plains, Somerset, Stratford, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, Newark’s University Hospital in Newark, and other affiliates. Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives.

Nice To Haves

  • Previous experience in single-molecule biophysics is strongly preferred.

Responsibilities

  • Engage in scientific communication, training of junior personnel, grant writing and manuscript preparation.
  • Participate in the evaluation of existing procedures, suggesting revisions where necessary and proposing new procedures where required.
  • Assists in the implementation of the programs and projects in special areas of interest to the laboratory.
  • Contribute to the development of performance standards, selection of methodology and instrumentation and coordination of the analytical, biochemical, physiology and instrumentation functions with the research areas to ensure conformance with the goals and objectives of the department.
  • Maintain accurate records of laboratory notebooks and research activity.
  • Review literature and prepare manuscripts and abstracts for submission.
  • Present findings at national meetings.
  • May also mentor graduate/undergraduate students.
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