A HIV-1 Envelope (Env) vaccine that elicits broadly neutralizing antibodies (bnAbs) has remained elusive, in part due to our limited understanding of the mechanisms of bnAb induction during natural infection. Dr. Williams has been awarded a NIH UM1 grant to develop new vaccine strategies that can induce more protective immune responses in the non-human primate (NHP) model by exploring innovative mRNA constructs for immunogen delivery that can elicit both protective and therapeutic B and T cell responses. Recently, Dr. Williams was also awarded a NIH U01 grant to develop new vaccine strategies that can induce antibodies in early-life capable of preventing HIV-1 infection in pediatric populations. This computational immunobiology postdoctoral position is appropriate for a candidate who is enthusiastic and willing to undertake multiple molecular biology and computational approaches to evaluate host immunity elicited by candidate HIV vaccines when administered prophylactically, and/or HIV vaccines when administered therapeutically in combination with novel immunotherapies. The Williams lab has state-of-the-art equipment for single cell omics assays and support for computing power for data analyses. Here at DHVI, we value collaborations, and pride ourselves in providing an excellent environment for academic and professional growth.
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Job Type
Full-time
Education Level
Ph.D. or professional degree
Number of Employees
101-250 employees