Post Doctoral.Post Doctoral.Associate
About The Position
The University of Pittsburgh is seeking a Postdoctoral Associate to join the laboratory of Dr. Silmara de Lima in the Department of Ophthalmology. The Postdoctoral Associate will lead projects to develop in vitro models to study genetic disorders affecting retinal ganglion cells. These studies will utilize human induced pluripotent stem cells (hiPSCs) and their differentiation into specialized retinal cell types. The ideal Candidate will have strong hands-on experience with 3D organoid cultures, particularly retinal organoids. Experience with high-content imaging, flow cytometry, and genome editing (CRISPR/Cas9) is highly preferred. Candidates should also have a strong understanding of human retinal development and retinal degenerative diseases, such as glaucoma. A proven record of scientific publication and the ability to present findings at internal and external meetings are expected. Duties and responsibilities include optimizing protocols for generating both 2D cultures and 3D retinal organoids, characterizing cellular phenotypes, and investigating mechanisms that affect retinal ganglion cells during development. The successful Candidate will integrate stem cell biology with ocular, developmental, and molecular biology approaches.
Requirements
- Ph.D. in Cell Biology, Developmental Biology, Neuroscience, Ophthalmology, or a related field
- Demonstrate the ability to troubleshoot complex, long-term differentiation protocols
- Be a proactive team player comfortable working in a fast-paced research environment
Nice To Haves
- 2–4+ years of postdoctoral or industry experience in human iPSC culture and differentiation
- Strong hands-on experience with 3D organoid cultures, particularly retinal organoids
- Experience with high-content imaging, flow cytometry, and genome editing (CRISPR/Cas9)
- Strong understanding of human retinal development and retinal degenerative diseases, such as glaucoma
- Proven record of scientific publication
- Ability to present findings at internal and external meetings
Responsibilities
- Optimizing protocols for generating both 2D cultures and 3D retinal organoids
- Characterizing cellular phenotypes
- Investigating mechanisms that affect retinal ganglion cells during development
- Integrating stem cell biology with ocular, developmental, and molecular biology approaches
Benefits
- Travel support is available for national conferences
- Participation in career development workshops -OACD workshops
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
