Post Doctoral Scientist - Gene Therapy

Nationwide Children's Hospital • Columbus, OH

1d

About The Position

Overview: Dr. Nizar Saad’s lab is seeking a postdoctoral scientist to join a translational research program advancing RNA-based and genome-editing therapies for rare genetic diseases. The lab develops RNA-, and CRISPR-based approaches for laminopathies and muscular dystrophies, using viral and non-viral delivery platforms (i.e., AAV and extracellular vesicles (EVs)). The lab also leads EV-based biomarker discovery efforts in muscular dystrophies. This position will require experience in EV and/or AAV isolation, purification, and characterization, -omics workflows, mouse work, including dosing and tissue collection. Experience in EV and/or AAV engineering is desired. Experience in cardiovascular or skeletal muscle biology is preferred. Additional details: NIH-funded grant and Saad Lab page. Job Description Summary: Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.

Requirements

• PhD or equivalent degree in relevant field of science, required.
• Research experience from PhD program, required.
• Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
• Excellent laboratory technical skills.
• Excellent computer skills.
• Skills in qualitative and quantitative research methods.
• Ability to proactively manage and drive projects.

Nice To Haves

• Experience in EV and/or AAV engineering is desired.
• Experience in cardiovascular or skeletal muscle biology is preferred.

Responsibilities

• Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor.
• Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program.
• Records and analyzes data generated by the research study.
• Assists in the development of hypotheses for further investigation from the results of the studies performed.
• Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals.
• Presents findings at local and national research forums.
• Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
• Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree