Portfolio and Business Operations Lead

Jobgether

17h • $220,000 - $350,000

About The Position

The Portfolio and Business Operations Lead will drive strategic planning, operational excellence, and resource optimization for a high-impact pre-clinical portfolio within a dynamic research environment. This role translates broad organizational strategies into actionable initiatives that accelerate early clinical development, while overseeing portfolio performance and cross-functional resource allocation. You will partner closely with senior leadership to enable data-driven decisions, maintain stakeholder alignment, and implement robust governance frameworks. This position requires strategic insight, analytical rigor, and strong communication skills to support innovation-driven programs and high-performing teams. The role offers an opportunity to influence global operations while working in a collaborative, matrixed environment focused on delivering meaningful value to patients.

Requirements

• Advanced academic or strategic background (MD, PhD, MBA) with at least 10 years of relevant experience in pharmaceuticals, biotech, or consulting, ideally in inflammation or related therapeutic areas.
• Proven experience leading change, implementing business/process/system improvements, and driving operational excellence.
• Strong portfolio and project management expertise with deep knowledge of early clinical development and PoC strategies.
• Demonstrated leadership in complex, global matrix organizations with the ability to influence senior stakeholders.
• Exceptional analytical skills, including performance assessment and decision-support insights.
• Executive-ready communication skills and high digital literacy to advocate data- and technology-enabled approaches.
• Compliance-focused mindset aligned with high-quality standards and regulatory requirements.

Responsibilities

• Drive strategic planning and execution for the pre-clinical portfolio, focusing on early clinical development initiatives.
• Monitor portfolio performance, risks, milestones, and key metrics to inform timely, data-driven decisions.
• Lead cross-functional resource planning and allocation to ensure successful delivery of portfolio objectives.
• Manage stakeholder alignment across leadership, cross-functional teams, and governance bodies.
• Track deliverables and integrate portfolio frameworks, including governance, milestones, and RACIs.
• Support the translation of strategy into actionable initiative roadmaps, including analytics, working sessions, and strategic communications.
• Oversee talent development, succession planning, and high-performance culture initiatives within the portfolio team.

Benefits

• Competitive base salary range: $220,000 – $350,000.
• Role-specific discretionary bonus and potential relocation support.
• Comprehensive benefits package including medical, dental, vision, and life insurance.
• Retirement plans and contribution programs.
• Paid time off and vacation policies to support work-life balance.
• Professional development opportunities and a collaborative, innovation-driven environment.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree