People Operations Manager

BillionToOne•Union City, CA

19h•Hybrid

About The Position

Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today. Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong. BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making. The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment. This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.

Requirements

5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
Strong expertise in benefits administration and vendor management
Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
Demonstrated ability to design and improve scalable processes and systems
Strong analytical skills with experience using data to drive decisions
Excellent project management, organizational, and prioritization skills
Strong communication skills with the ability to influence and partner across levels
High attention to detail, sound judgment, and a proactive mindset
“Scrappy,” solutions-oriented approach with a focus on continuous improvement

Nice To Haves

Previous experience in start-up is highly desired

Responsibilities

Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed

Benefits

Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.