Omics & Bioinformatics Scientist

Becoming•San Francisco, CA

About The Position

Becoming is building Developmental Intelligence: AI for predicting how organisms change over time. Most experimental systems fail when metabolic demands become too high. We are building systems that don’t — by combining engineered metabolic environments, sensing, control, and software into tightly integrated products that operate reliably over long time horizons. Hardware is core to our platform. It must work continuously, predictably, and under real biological constraints. We are hiring an Omics & Bioinformatics Scientist (Wet Lab + Data Pipelines) who can operate across omics experiment generation, perturbation experiments, computational analysis, and biological data engineering. This is not a purely computational role. You will run omics experiments at the bench, generate high-quality datasets, and build the pipelines that convert raw biological data into structured datasets usable by machine learning systems. The role spans transcriptomics, epigenomics, and proteomics. You will design and execute omics experiments, analyze the resulting datasets, and build reproducible data pipelines so these datasets can be integrated with imaging, physiological, and experimental metadata from Becoming’s systems. You will work closely with developmental biologists generating engineered developmental systems and with AI researchers building predictive models of development. Your responsibility is to ensure that biological data is experimentally robust, computationally analyzable, and programmatically accessible. This role requires someone comfortable owning the full lifecycle of biological data: experimental design → omics generation → analysis → pipelines → structured datasets.

Requirements

PhD in Genomics, Bioinformatics, Computational Biology, Systems Biology, Proteomics, or related field
Demonstrated experience performing omics experiments at the bench (library preparation or proteomics sample preparation)
Experience designing or executing biological perturbation experiments
Experience analyzing transcriptomics or single-cell omics datasets
Familiarity with proteomics workflows and mass-spectrometry datasets
Proficiency in Python for biological data analysis
Experience with tools such as Scanpy, Seurat, Bioconductor, or proteomics analysis software
Ability to design experiments and interpret results in collaboration with experimental scientists

Nice To Haves

Experience with LC-MS/MS proteomics workflows and analysis
Experience integrating multi-modal datasets (transcriptomics, proteomics, imaging, physiology)
Experience building data pipelines or data infrastructure for biological datasets
Experience with developmental biology systems (embryos, stem cells, organoids, or early developmental models)
Experience working with large genomics or proteomics datasets

Responsibilities

Design and execute omics experiments, including sample preparation and sequencing or mass-spectrometry library generation
Perform wet-lab protocols for single-cell RNA-seq, bulk RNA-seq, ATAC-seq, spatial transcriptomics, and proteomics assays
Design and run perturbation experiments (e.g., genetic, chemical, environmental) to probe developmental systems
Prepare samples for mass spectrometry-based proteomics (e.g., LC-MS/MS workflows)
Develop and maintain bioinformatics pipelines for processing omics datasets
Perform quality control, normalization, and downstream analysis of transcriptomic and proteomic datasets
Map cell states and developmental trajectories across time
Work with experimental teams to design experiments that generate informative, analyzable datasets
Build data pipelines to process, store, and structure biological datasets
Integrate omics data with imaging, physiological measurements, and experimental metadata
Structure datasets so they can be used directly by machine learning and modeling systems