Bioinformatics Engineer - Multi-omics

Prima MenteSan Francisco, CA
2dOnsite

About The Position

Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai. Role focus - Multi-omics Clearly articulate and interrogate meaningful biological hypotheses for marker and target discovery related to neurological diseases.

Requirements

  • You want to redefine what’s possible at the frontier of AI and biology.
  • You have experience uncovering novel biology from multi-omic multi-modal data as well as top tier publications and / or patents.

Nice To Haves

  • Commercial experience generating insights from biological data (genomics, epigenetics, transcriptomics, proteomics, ATAC-Seq).
  • Operational software engineering skills: the ability to write high-quality code to be the backbone of our software stack.
  • Experience with end-to-end tools used to process multi-omic data from raw data all the way to analytical outputs, including but not limited to NextFlow, Seqera.
  • Strong working knowledge with cloud computing environments, including but not limited to AWS.
  • Familiar with data wrangling, engineering, analysis, and visualisation libraries using Python or Julia, Spark, Hadoop, NoSQL.
  • Application of artificial intelligence approaches and experience applying them to a biological context.
  • Top tier publications.
  • Patent experience.

Responsibilities

  • Feature engineering and dataset preparation for downstream machine learning as well as foundational AI training and application.
  • Analysis of in-house wet lab experiments with the purpose to generate proprietary methods and data for our models.
  • Multi-omic bioinformatics pipeline development.
  • Develop and manage specific external research collaborations with academic and industrial partners specific to AD biology.
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