Manufacturing Technician

Nautilus Biotechnology•San Carlos, CA

32d

About The Position

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines. We are hiring a Manufacturing Technician to join our growing team. This technician will support the assembly and build of our instrument platform. This role will focus on hands-on assembly of complex electromechanical systems including mechanical structures, fluidic systems, and internal electrical wiring within a complex instrument chassis. The Manufacturing Technician will play a critical role in executing prototype and pilot builds, supporting the transition from engineering development to scalable manufacturing. The ideal candidate is comfortable working in a fast-paced development environment and has experience assembling complex scientific or electromechanical instrumentation.

Requirements

3–7+ years of experience assembling complex electromechanical systems
Experience working with mechanical assemblies, fluidics, and electrical wiring
Experience working in prototype, NPI, or pilot manufacturing environments
Strong attention to detail and assembly quality
Ability to work independently after initial training
Comfortable working in a fast-paced development environment
Ability to identify and escalate build issues quickly
Strong communication skills and ability to work cross-functionally with engineering teams

Nice To Haves

Biotechnology / life sciences instrumentation
Medical devices
Analytical instrumentation
Semiconductor equipment
Aerospace instrumentation

Responsibilities

Perform hands-on assembly of complex electromechanical instruments
Assemble mechanical chassis, structural components, and internal subassemblies
Install and route fluidic systems, including tubing, manifolds, pumps, and valves
Install and route electrical wiring and harnesses within instrument enclosures
Integrate mechanical, electrical, and fluidic subsystems within the instrument chassis
Execute engineering prototype builds, design verification builds, and pilot production builds
Follow detailed work instructions and assembly procedures
Verify correct installation and alignment of components during assembly
Escalate assembly issues or deviations to engineering or operations teams
Support troubleshooting and rework activities when required
Complete required manufacturing documentation including Device History Records (DHR), build travelers, traceability records
Record serial numbers and part traceability information
Document deviations or observations during builds
Provide redlines or suggested improvements to assembly instructions
Provide feedback to engineering and operations teams regarding build challenges or assembly issues
Document observations that may improve manufacturability or assembly efficiency
Support continuous improvement of assembly processes during pilot builds