Manufacturing Associate II

Immatics N.V.•Houston, TX

57d•Onsite

About The Position

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. We are seeking a Manufacturing Associate II to support our CMC-GMP Manufacturing team. The Manufacturing Associate will be responsible for performing complex, highly specialized and time sensitive technical cell manipulation and testing procedures on irreplaceable cellular products during clinical manufacturing. This is a critical position and may require working overtime, after-hours, weekends, or holidays to ensure business continuity.

Requirements

Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent.
Associate Degree in Biology, Biochemistry, Biotechnology, Biomanufacturing or other related field.
Two (2) to Four (4) years of cell therapy manufacturing experience.

Nice To Haves

Bachelor's Degree in Biology, Biochemistry, Biotechnology or other related field.
Four (4) years of cell therapy manufacturing experience.

Responsibilities

Fulfill the operator and verifier roles in performing cell growth and manipulation procedures such as cell enrichment, cell culture, cellular product cryopreservation, cell product thaw/wash.
Accurately perform procedures in compliance with FDA's Good Laboratory Practices, Good Manufacturing Practices, Good Tissue practices, as well as standards set by other accreditation agencies including but not limited to FACT, CAP, and CLIA.
Adhere to ALCOAC++ and cGDocP requirements while accurately performing procedures and maintaining documentation in compliance with SOPs.
Document deviations and events, notify supervisor and quality management personnel in a timely manner and assist in investigation of root cause and any required corrective actions.
Responsible for aseptic handling of reagents and products to ensure the integrity and sterility of cellular products until final infusion to the patient. Must adhere to special cleaning and gowning requirements for the facility requiring specialized gowning such as masks, sterile jumpsuits, hair and shoe covers.
Ability to work productively and to participate in a highly creative and fast-paced environment
Independently perform calculations to determine cell viability, dilutions, and cell concentrations.
Completes all appropriate logs and trackers.
Maintains GMP cleanliness: autoclaving, bleaching liquid waste, removing waste, general cleanliness and organization of the office and facility.
Maintains knowledge regarding donor evaluation, screening and testing, labeling and product acceptability and release criteria.
Conducts activities to support study plans, and IQ/OQ/PQs.
Provide input or feedback regarding change controls, WI, SOPs, study plans, reports, deviations, OOS/OOE, and CAPA's as directed.
Performs routine equipment maintenance and troubleshooting.
Prepares and presents manufacturing summaries, as needed.

Benefits

Competitive rates for Health, Dental, and Vision Insurance
4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
Sick Time Off - 56 hours
12 Paid Holidays
100% Employer-Paid Life Insuranceâ¯up to at 1x annual salary
100% Employer Paid Short- and Long-Term Disability Coverage
401(k) with Immediate Eligibilityâ¯ & company match…
You are eligible for 401(k) plan participation as of your first paycheck.
The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid Parental Leaveâ¯for eligible employees. (3 weeks)
Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illnessâ¯Employee Paid Identity Theft Protection and Pet Insurance.
Opportunities to work with leading experts in the field of T-cell immunotherapy.
Company provided learning and development opportunities
Fast paced, high demand collaborative and dynamic environment.