Manager I - Large Molecule (LC/MS)

BioAgilytix•Durham, NC

About The Position

At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You’ll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them. Our Liquid Chromatography/Mass Spectrometry (LC/MS) team is seeking a Manager I to serve as Bioanalytical Project Manager (BPM)/Principal Investigator (PI), overseeing all aspects of bioanalytical studies—including project scope definition, proposal preparation, timelines, scheduling, budget, and revenue management. This role is best suited for someone with deep expertise in method development, GxP-compliant validation, and both targeted and untargeted analysis using chromatography and mass spectrometry, combined with strong communication skills and the confidence to engage with external clients. At our organization, we're dedicated to pushing the boundaries of analytical science. Our LC/MS team leverages the synergy between liquid chromatography (LC) and mass spectrometry (MS) to revolutionize how we understand and quantify compounds in complex samples. With a steadfast commitment to excellence and innovation, we tackle challenges across the spectrum of drug discovery to clinical diagnostics, driving advancements that shape the future of healthcare.

Requirements

Bachelor’s degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than 12 years’ experience in a scientific laboratory environment; or Master’s degree in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than ten (10) years’ experience in a scientific laboratory environment; or PhD in molecular biology, biochemistry, immunology, biotechnology, or related field with not less than eight (8) years’ experience in a scientific laboratory environment
Knowledge of regulatory guidance and industry best practices for LC/MS, and other large molecule assays
Demonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
Advanced capabilities in data analysis, data visualization statistical analysis
Microsoft Word, Excel, Sciex OS/Analyst, MassLynx, XCalibur, Chromeleon, Watson LIMS, JMP, Graphpad Prism
GDP, GLP, GCLP, GCP
Expertise in development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench work
Demonstrated experience in a supervisory role leading teams to meet objectives while adapting to competing demands, tight deadlines, and a fast-paced environment
Must work effectively within team to meet objectives under time constraints
A knack for designing efficient and impactful experiments
Experience working in a regulated environment, with a thorough understating of GDP, GLP, GCLP, GCP
Independence, enthusiasm, openness, and adaptability
Demonstrated effective communication skills
The ability to inspire others to do their best work and drive results
Excellent customer service skills (internal and external)

Responsibilities

Lead team(s) developing and validating LC/MS bioanalytical assays for support of preclinical, clinical and product release studies.
Motivating team by inspiring employees to achieve goals and aligning employee goals with company strategy by understanding trends and operations, managing departmental budgets and resources, and being the expert in using tools/software relevant to the team.
Work closely with clients to assure successful on time execution of assays, validation, and sample analysis under GxPs.
Prioritizing tasks and managing schedules efficiently.
Meet regularly with lab management to ensure instrument resources and employees are utilized effectively across all teams.
Responsible for team performance and outcomes.
Leading teams through transitions and new initiatives.
Design and execute experiments efficiently and assign tasks appropriately to employees based on skills.
Anticipating and mitigating potential problems and handling disputes calmly and fairly
Present data and posters.
Conduct group team meetings to understand employee’s input and concerns, give constructive and timely feedback, and implement 1:1 meetings with employees on a regular basis.
Hiring and building a team that is knowledgeable and cooperative by investing in the employees’ professional growth, setting goals and evaluating results.
Identify new analytical techniques and technologies and lead their implementation.
Review analytical instrument and equipment calibration, qualification and maintenance records.
Perform statistical analysis.
Write and review reports and prepare SOPs.
Lead regularly scheduled client meetings to ensure effective communication and manage client expectations.
Provide client satisfaction and great science.
Achieve corporate revenue targets.