Manager, Clinical Research Imaging Operations

OneOncology•Nashville, TN

About The Position

Tennessee Oncology, one of the nation’s largest, community-based cancer care specialists, is home to one of the leading clinical trial networks in the country. Established 1976 in Nashville, Tennessee Oncology’s mission remains unchanged: To provide access to high-quality cancer care and the expertise of clinical research for all patients, at convenient locations within their community and close to their home. Our growing network of physicians and locations is based on this mission. Tennessee Oncology is committed to advancing both the science of detection and targeted treatments, and to making these advances available to every patient. We believe caring for cancer patients is a privilege. Why Join Us? We are looking for talented and highly-motivated individuals who demonstrate a natural desire to support the meaningful work of community oncologists and the patients we serve. Job Description: The Manager, Clinical Research Imaging Operations is responsible for strategic oversight, operational management, and quality execution of all imaging-related activities for oncology clinical trials conducted at the site. This role serves as the subject matter expert for protocol-required imaging, tumor response assessments, and imaging workflows across studies, ensuring compliance with protocol requirements, sponsor expectations, and regulatory standards. The Clinical Research Imaging Operations Manager partners closely with investigators, radiology, site research staff, and sponsors/CROs to ensure imaging endpoints are collected accurately, consistently, and on scheduled to support trial integrity and patient safety.

Requirements

Bachelor’s degree required
Minimum of 3 years of clinical research experience with direct involvement in imaging-related trial activities required
Strong knowledge of FDA regulations, GCP, ICH guidelines, and IRB processes
Demonstrated understanding of tumor response assessments and oncology imaging endpoints
Excellent organizational, communication, and time-management skills
Ability to manage multiple projects simultaneously and work effectively under tight deadlines

Nice To Haves

Previous management experience preferred

Responsibilities

Ensures compliance with federal, state, and local regulations, as well as Good Clinical Practice (GCP) guidelines and study-specific protocols
Provides end-to-end oversight of imaging activities across oncology clinical trials, including baseline, on-treatment, and follow-up assessments
Ensures imaging workflows are standardized, efficient, and aligned with protocol-specific requirements
Serves as the primary escalation point for imaging-related issues, deviations, or sponsor inquiries
Reviews oncology protocols to identify all imaging requirements, including modality, timing, anatomical coverage, contrast use, and response criteria
Translates protocol imaging requirements into operational workflows for research and radiology teams
Participates in feasibility assessments to evaluate imaging complexity, site capability, and resource needs
Demonstrates working knowledge of oncology response criteria (e.g., RECIST 1.1, iRECIST, Lugano, RANO)
Supports investigators and research staff in understanding response assessment requirements and documentation expectations
Ensures imaging data is collected, submitted, and stored in compliance with protocol, GCP, and regulatory requirements
Monitors imaging related deviations and implements corrective and preventive actions as needed
Identifies trends in imaging errors or delays and leads process improvement initiatives
Collaborates with data management and clinical research teams to ensure imaging data aligns with clinical data timelines
Provides functional guidance and mentorship to imaging coordinators or research staff supporting imaging activities
Develop and deliver training related to protocol imaging requirements, response criteria, and workflow expectations
Conducts performance evaluations, provides feedback, and fosters professional development opportunities for direct reports
Ensures appropriate staffing levels for site operations and facilitates the recruitment of new team members as needed
Departmental supply ordering
Protects the rights, safety, and welfare of patients
Maintains a professional approach respecting the dignity and confidentiality of patients
Maintains a good attendance record and reports to work on time
Maintains a professional attitude and appearance
Travel to all research site offices as necessary
Performs other duties as assigned