Local Study Manager

AstraZeneca

23h • $112,154 - $168,232

About The Position

Local Study Manager

Key responsibilities Coordinate operational aspects of AstraZeneca–sponsored studies from study start‑up through CSR and/or publication. Lead and/or participate in activities that ensure the quality, consistency, and integration of study data to agreed time, cost, and quality objectives. Act as an interface with field monitoring CRAs, the Local Study Associate Director (LSAD), and the Global Study Team (GST). Establish and maintain effective interactions with key stakeholders, including the GST, strategic partners, academic clinics, investigational study sites, and external service providers (third‑party vendors). Identify and resolve operational feasibility issues. Facilitate study start‑up activities. Ensure operational deliverables are met within agreed timelines, budget, and quality. Implement globally agreed Development Operations strategies, including relevant processes and technical systems related to study operations. Contribute to the development, maintenance, and amendment of Operations documents as appropriate. Ensure timely entry and/or updating of relevant information in AstraZeneca tracking and communication systems (for example, VCV). Liaise with Clinical Supply Chain and/or external service providers to ensure adequate and timely supply of study materials and investigational product. Contribute to the planning and conduct of local internal and external meetings (for example, Investigator and Monitor meetings). Monitor study conduct and progress, proactively identifying issues that may impact study delivery, quality, timelines, or budget, and work with the LSAD to resolve them. Contribute, as required, to steering committees, submission assembly teams, regulatory defence teams, and advisory boards. Support team productivity and efficiency by providing direction, sharing best practices, and facilitating positive team dynamics. Provide input into non‑drug project work, including training activities and the development or refinement of procedures. Essential qualifications, skills and experience Bachelor of Science degree in a related discipline (preferably medical, biological, or health‑related sciences), or equivalent relevant work experience in directly related fields. 3+ years of experience working on clinical studies across different phases of drug development. Relevant industry or healthcare experience. Strong organizational and analytical skills. Communication skills Solid understanding of the clinical study and drug development process, and of GCP/ICH guidelines as they relate to operational study activities. Proficiency with standard computer applications and an ability to work effectively in an e‑enabled environment. Excellent spoken and written English. Demonstrated ability and willingness to work and lead cross‑functionally with internal and external partners, including on global studies, across different phases of development and therapy areas. Good understanding of clinical data flow. Ability to develop and apply advanced computer skills to increase efficiency in day‑to‑day tasks. Demonstrated project management skills (for example, experience leading a delivery team). Excellent mentoring and coaching skills, and the ability to support the development of others. Ability to manage change with a positive approach, seeing change as an opportunity to improve performance and add value. Ability to seek out and champion more efficient and effective methods/processes to deliver quality clinical trials with reduced timelines and budgets. Strong analytical and problem‑solving skills. Demonstrated ability to prioritize and manage multiple tasks with competing deadlines. Familiarity with risk‑based monitoring approaches, including remote monitoring. Good cultural awareness. Additional skills and competencies Excellent verbal and written communication and presentation skills. Ability to work independently as well as effectively within a team environment. Strong interpersonal skills and proven ability to facilitate teamwork and collaboration. Willingness and ability to travel domestically and internationally, as needed. Sound knowledge of GCP and AstraZeneca procedural documents as they pertain to study delivery systems and processes. Proactive identification of risks and issues, with the ability to propose and drive solutions. High standards of professionalism, using tactful persuasion to obtain desired outcomes while maintaining effective and positive organizational relationships. Willingness and ability to develop knowledge in relevant therapy areas through experience and review of scientific literature, and to quickly learn new therapy areas when required. Ability to prepare and deliver study‑related training materials. Ability to plan, coordinate, and facilitate internal and external meetings effectively. Strong organizational and time‑management skills, excellent attention to detail, and ability to work in a high‑volume environment with shifting priorities. Ability to work effectively with remote collaborators. Team‑oriented and flexible, with the ability to respond quickly to changing demands and opportunities. Clinical trials CRMs – data base systems The annual base pay (or hourly rate of compensation) for this position ranges from $112,154.40 - 168,231.60 USD Annual. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans Date Posted 10-abr-2026 Closing Date 16-abr-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Requirements

• Bachelor of Science degree in a related discipline (preferably medical, biological, or health‑related sciences), or equivalent relevant work experience in directly related fields.
• 3+ years of experience working on clinical studies across different phases of drug development.
• Relevant industry or healthcare experience.
• Strong organizational and analytical skills.
• Communication skills Solid understanding of the clinical study and drug development process, and of GCP/ICH guidelines as they relate to operational study activities.
• Proficiency with standard computer applications and an ability to work effectively in an e‑enabled environment.
• Excellent spoken and written English.
• Demonstrated ability and willingness to work and lead cross‑functionally with internal and external partners, including on global studies, across different phases of development and therapy areas.
• Good understanding of clinical data flow.
• Ability to develop and apply advanced computer skills to increase efficiency in day‑to‑day tasks.
• Demonstrated project management skills (for example, experience leading a delivery team).
• Excellent mentoring and coaching skills, and the ability to support the development of others.
• Ability to manage change with a positive approach, seeing change as an opportunity to improve performance and add value.
• Ability to seek out and champion more efficient and effective methods/processes to deliver quality clinical trials with reduced timelines and budgets.
• Strong analytical and problem‑solving skills.
• Demonstrated ability to prioritize and manage multiple tasks with competing deadlines.
• Familiarity with risk‑based monitoring approaches, including remote monitoring.
• Good cultural awareness.

Nice To Haves

• Excellent verbal and written communication and presentation skills.
• Ability to work independently as well as effectively within a team environment.
• Strong interpersonal skills and proven ability to facilitate teamwork and collaboration.
• Willingness and ability to travel domestically and internationally, as needed.
• Sound knowledge of GCP and AstraZeneca procedural documents as they pertain to study delivery systems and processes.
• Proactive identification of risks and issues, with the ability to propose and drive solutions.
• High standards of professionalism, using tactful persuasion to obtain desired outcomes while maintaining effective and positive organizational relationships.
• Willingness and ability to develop knowledge in relevant therapy areas through experience and review of scientific literature, and to quickly learn new therapy areas when required.
• Ability to prepare and deliver study‑related training materials.
• Ability to plan, coordinate, and facilitate internal and external meetings effectively.
• Strong organizational and time‑management skills, excellent attention to detail, and ability to work in a high‑volume environment with shifting priorities.
• Ability to work effectively with remote collaborators.
• Team‑oriented and flexible, with the ability to respond quickly to changing demands and opportunities.
• Clinical trials CRMs – data base systems

Responsibilities

• Coordinate operational aspects of AstraZeneca–sponsored studies from study start‑up through CSR and/or publication.
• Lead and/or participate in activities that ensure the quality, consistency, and integration of study data to agreed time, cost, and quality objectives.
• Act as an interface with field monitoring CRAs, the Local Study Associate Director (LSAD), and the Global Study Team (GST).
• Establish and maintain effective interactions with key stakeholders, including the GST, strategic partners, academic clinics, investigational study sites, and external service providers (third‑party vendors).
• Identify and resolve operational feasibility issues.
• Facilitate study start‑up activities.
• Ensure operational deliverables are met within agreed timelines, budget, and quality.
• Implement globally agreed Development Operations strategies, including relevant processes and technical systems related to study operations.
• Contribute to the development, maintenance, and amendment of Operations documents as appropriate.
• Ensure timely entry and/or updating of relevant information in AstraZeneca tracking and communication systems (for example, VCV).
• Liaise with Clinical Supply Chain and/or external service providers to ensure adequate and timely supply of study materials and investigational product.
• Contribute to the planning and conduct of local internal and external meetings (for example, Investigator and Monitor meetings).
• Monitor study conduct and progress, proactively identifying issues that may impact study delivery, quality, timelines, or budget, and work with the LSAD to resolve them.
• Contribute, as required, to steering committees, submission assembly teams, regulatory defence teams, and advisory boards.
• Support team productivity and efficiency by providing direction, sharing best practices, and facilitating positive team dynamics.
• Provide input into non‑drug project work, including training activities and the development or refinement of procedures.

Benefits

• Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level