Lead Systems Engineer

McKesson

3d

About The Position

It’s More Than a Career, It’s a Mission. Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day. Our Mission People who live with cancer – those who work to prevent it, fight it, and survive it – are at the heart of every decision we make. Bringing the most innovative medical minds together with the most passionate caregivers in their communities, we are transforming care and personalizing treatment. Through clinical excellence and cutting-edge research, SCRI is redefining cancer care around the world. The Lead Systems Engineer serves as the technical authority and solution architect for complex systems and application ecosystems. This role leads the design, integration, validation, and optimization of scalable, compliant solutions that transform manual processes into automated systems, ensuring alignment with technical, regulatory, schedule, and budgetary requirements. The Lead Systems Engineer provides technical leadership across cross-functional teams, mentors engineers, and drives innovation through AI-enabled capabilities.

Requirements

• Bachelor's or Master's degree in Systems Engineering, Electrical Engineering, Computer Science, or a related field.
• Proven experience (10+ years) in systems engineering, with a track record of leading complex projects.
• Extensive knowledge of advanced engineering principles, theories, and concepts.
• Strong analytical and problem-solving skills with the ability to address complex challenges.
• Excellent leadership and communication skills, with experience mentoring and guiding teams.
• Proficiency in system design tools and methodologies.
• Advanced application and systems engineering principles.
• Clinical research systems and regulated environments.
• Veeva platform architecture, configuration, and integration (required).
• Software development lifecycle (SDLC), validation, and compliance standards.
• Proficiency with Veeva Systems, particularly Veeva Clinical Operations (required) and Veeva Vault modules for document and regulatory management.
• Experience with clinical system interoperability and data exchange.
• Cloud platform experience (AWS, Azure, or GCP).
• Agile and DevOps delivery methodologies.
• Ability to manage multiple initiatives in a fast-paced environment.
• Strong collaboration skills within cross-functional technical teams.
• Solution and system architecture design.
• Complex system integration and troubleshooting.
• Technical leadership and mentoring.
• Stakeholder communication and influence.
• AI-enabled solution design and automation.

Responsibilities

• System Design & Integration: Lead the deployment of enterprise and clinical engineering solutions that convert manual business processes into automated, validated systems.
• Architect, integrate, and validate complex application ecosystems, with primary accountability for Veeva Clinical Operations and related Veeva platforms.
• Ensure system designs meet performance, reliability, scalability, security, and regulatory requirements (e.g., GxP, Part 11).
• Translate product and business requirements into cohesive end-to-end system solutions across multiple platforms.
• Establish and enforce engineering standards, design patterns, and integration approaches.
• Partner with support teams to improve reliability, monitoring, and operational maturity.
• Technical Leadership: Serve as the technical lead for cross-functional delivery teams, providing architectural direction and technical decision-making.
• Mentor and develop junior and senior engineers, promoting engineering excellence, best practices, and continuous improvement.
• Analysis & Problem Solving: Perform functional, timeline, and trade-off analyses to evaluate solution options and recommend optimal approaches.
• Independently resolve highly complex technical issues requiring advanced judgment, creativity, and systems thinking.
• Balance cost, risk, supportability, and compliance in all technical decisions.
• Program Management: Partner with Project and Program Managers to oversee the full solution lifecycle from requirements through implementation and post-go-live support.
• Coordinate internal and external technical resources, including vendors and platform partners.
• Innovation & Development: Leverage Artificial Intelligence (AI) to enhance system capabilities, automate processes, and improve decision-making.
• Contribute to the development of innovative architectural patterns integrating AI into clinical and enterprise systems.
• Continuously identify opportunities to apply emerging technologies to improve efficiency, scalability, and data quality.

Benefits

• We care about the well-being of the patients and communities we serve, and that starts with caring for our people. That’s why we have a Total Rewards package that includes comprehensive benefits to support physical, mental, and financial well-being.
• Our Total Rewards offerings serve the different needs of our diverse colleague population and ensure they are the healthiest versions of themselves.
• For more information regarding benefits through our parent company, McKesson, please click here.
• As part of Total Rewards, we are proud to offer a competitive compensation package. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets.
• In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level