Invent Fellow - PhD, Research

Seattle Children's•Seattle, WA

4d•$80,000 - $80,000

About The Position

The post-doctoral scholar will envision research strategies that could ultimately benefit children with medical or mental health disorders or diseases. In consultation with the mentor whose lab they will join and other mentors with clinical or biotechnology expertise, the scholar will establish a plan for engineering or creating candidate therapeutics or improving existing therapeutics. Possible areas of therapeutic discovery and development include gene therapy, cellular therapeutics (e.g., CAR-T cells), or protein therapeutics (e.g., antibody or peptide therapeutics). Initial experiments may focus on target validation or proof-of concept efficacy studies. Later work may focus on maximizing potential therapeutic efficacy and minimizing potential toxicity. When appropriate, scholars will focus on molecules or cells that have potential to enter human clinical trials. Experiments will often involve collaboration with other scientists to create compelling data that drives subsequent research and development decisions. Scholars will engage in biotech-oriented team science that involves milestone-driven research and will collaborate with their mentors to make clear "Go/No-Go" decisions that mirror biotech mindset and processes. Postdoctoral scholars will take the lead on preparing manuscripts that report their results and work toward the goal of becoming nationally competitive for careers in academia or industry. Up to 20% of time will be devoted to coursework designed to develop skills in drug discovery and development, regulatory affairs, and intellectual property management.

Requirements

Doctorate degree (PhD/DVM/MD) in specialty area from an accredited university training program
Experience using basic research techniques of specialty area

Nice To Haves

Experience in protocol or manuscript development and in grant writing

Responsibilities

Envision research strategies to benefit children with medical or mental health disorders.
Establish a plan for engineering or creating candidate therapeutics or improving existing therapeutics.
Focus on target validation or proof-of concept efficacy studies.
Maximize potential therapeutic efficacy and minimizing potential toxicity.
Focus on molecules or cells that have potential to enter human clinical trials.
Collaborate with other scientists to create compelling data.
Engage in biotech-oriented team science that involves milestone-driven research.
Prepare manuscripts that report their results.
Work toward the goal of becoming nationally competitive for careers in academia or industry.
Devote up to 20% of time to coursework designed to develop skills in drug discovery and development, regulatory affairs, and intellectual property management.