Intern, Skeletal Cell Biology Research

BioMarin Pharmaceutical Inc.San Rafael, CA
64d$24 - $27Hybrid

About The Position

The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. Over the course of 10 - 12 weeks our interns gain industry experience while working alongside our talented team on meaningful projects. BioMarin’s Research and Early Development (RED) team focuses on discovering and advancing innovative therapies for rare genetic conditions. We work across multiple scientific disciplines to translate early research into potential treatments that can make a meaningful impact for patients. The Skeletal Therapeutic Area is dedicated to developing therapies aimed at improving outcomes for individuals with skeletal conditions. Interns will gain exposure to research techniques, contribute meaningful work to support active research programs, and learn how early-stage drug development happens in a collaborative environment. JOB DESCRIPTION/PROJECT: Develop reporter cell lines to monitor gene regulation in response to treatments that alter signaling pathways. Incorporate clinically relevant genetic variants into these models to study their impact on RNA processing and stability, including evaluation of cellular RNA quality-control mechanisms.

Requirements

  • Hands-on experience working in a mammalian cell culture lab, including aseptic techniques
  • Basic understanding of RNA biology
  • Ability to follow protocols and standard operating procedures with precision
  • Strong organizational skills and commitment to accurate record-keeping
  • A proactive, collaborative attitude with a willingness to learn new scientific techniques
  • Undergraduate student in their 3rd or 4th year pursuing a degree in a scientific discipline.
  • Must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program.
  • Must be available to work full time, 40 hours a week.
  • Must be currently enrolled as a full-time student at an accredited U.S. based university or college and enrolled in the fall term after the completion of the internship OR have graduated within 1 year of the start of the program.
  • Must be able to relocate if necessary and work at the designated site for the duration of the internship for on-site, hybrid roles.

Nice To Haves

  • Experience with qPCR or ddPCR for gene expression analysis
  • Familiarity with Western blot or ELISA for protein-level studies
  • Ability to analyze and visualize data using graphing or statistical software

Responsibilities

  • Develop reporter cell lines to monitor gene regulation in response to treatments that alter signaling pathways.
  • Incorporate clinically relevant genetic variants into these models to study their impact on RNA processing and stability, including evaluation of cellular RNA quality-control mechanisms.

Benefits

  • Paid hourly wage, paid company holidays, and sick time
  • Apply skills and knowledge learned in the classroom to on-the-job experiences
  • Comprehensive, value-added project(s)
  • Develop skills specific to your major.
  • Opportunities for professional development by building relationships and learning about other parts of the business.
  • Participate in company all hands meetings, monthly community lunches
  • Corporate office amenities such as: 24/7 on-site gym, coffee truck, snacks
  • Access to Employee Resource Groups
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