Intern, Research

Fred Hutchinson Cancer Center•Seattle, WA

6d•$21 - $30•Onsite

About The Position

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Human Biology Division cultivates interdisciplinary research to advance understanding of human biology and the complex problems of neoplasia and other human diseases. The division is structured to foster laboratory-based and computational research at the interface of basic, clinical and population sciences. The Holland Lab internship provides research training in neuro-oncology, with a focus on understanding the molecular and cellular mechanisms driving glioblastoma. The intern will contribute to projects using genetically engineered mouse models through the RCAS/tv-a system to study tumor progression and therapeutic response. The intern will gain experience in laboratory animal handling and treatment, histological tissue processing, quantitative image analysis, and cell culture techniques. The internship will also provide experience in experimental design, data analysis, and scientific communication. This is a part time, in-person internship.

Requirements

High school diploma or equivalent.

Nice To Haves

Experience analyzing MRI data.
Conceptual understanding of cellular and molecular neuroscience.
Good written and verbal communication.

Responsibilities

Establish a comprehensive understanding of glioblastoma biology, with emphasis on keyoncogenic drivers and the use of the RCAS/tv-a system to model disease progression and evaluate therapeutic strategies.
Acquire foundational skills in cell culture, including sterile technique, cell maintenance, experimental manipulation of cultured cells, and preparing cells for injection in mice.
Develop proficiency in laboratory animal management, including the handling, treatment, and monitoring of mice for experimental studies.
Generate and analyze histological data by preparing tissue samples, producing immunohistochemical images, and quantitatively assessing treatment using QuPath.
Strengthen scientific communication skills by effectively conveying experimental progress and results to people at different levels of experience.
Develop skills in experimental design, data organization, and reproducible research practices, including proper controls, documentation, and data management.
Gain experience working collaboratively in a research environment, incorporating feedback from peers, postdocs, and PI's