Intern - Intelligent Topology Optimization for Next Generation Bioprocess Design

Sartorius Stedim • Marlborough, MA

3d

About The Position

In this Corporate Research internship, you will contribute to the development of next‑generation bioprocessing technologies—integrating computational modeling, advanced simulation, and data‑driven optimization approaches. The role focuses on applying multiphysics simulation, computational fluid dynamics (CFD), and algorithmic/ML‑driven topology and geometry optimization to accelerate the design of innovative systems such as the next generation of bioreactors, flow kits, mixers, and microfluidic devices. You will design, execute, and analyze computational studies; develop and refine simulation tools; and support the translation of predictive models into actionable engineering designs. This role involves collaboration with internal Research teams, including fluidics engineering, additive manufacturing, and advanced materials groups, as well as external experts, to advance emerging bioprocessing concepts.

Requirements

• Pursuing a M.S., or Ph.D. in Chemical Engineering , Bioengineering , Mechanical Engineering , Computer Science , Computational Engineering , or a related technical discipline.
• Strong understanding of fluid dynamics , heat transfer , and mass transfer fundamentals.
• Experience with multiphysics modeling tools (e.g., COMSOL Multiphysics , ANSYS Fluent , MStar‑CFD, SolidWorks ).
• Experience in developing scripts or codes for simulation automation or optimization (e.g., Python , MATLAB , C++ , or similar).
• Familiarity with machine learning methods , design optimization , numerical methods , or data‑driven modeling .
• Ability to collaborate with diverse engineering teams (fluidics, additive manufacturing, advanced materials, optical/sensor engineering, and chemical engineering).

Nice To Haves

• Exposure to bioprocessing or life‑science systems (bioreactors, microfluidics, filtration, or mixing technologies) is a plus.
• Strong analytical and mathematical skills; demonstrates robust problem‑solving capability.
• Ability to work independently and cooperatively within a multidisciplinary research environment.
• Strong initiative, intellectual curiosity, and results‑oriented mindset.
• Excellent written and verbal communication skills for conveying computational findings to audiences with varying technical backgrounds.
• Experience with documentation and version‑control systems (e.g., Git) is a plus.

Responsibilities

• Develop and execute multiphysics and CFD simulations to investigate fluid flow, mass transfer, and heat transfer phenomena in bioprocessing systems.
• Apply topology optimization , geometry optimization , and machine learning–driven algorithms to guide the design of bioreactors, mixers, and microfluidic platforms.
• Create, implement, and validate custom algorithms for multi‑objective optimization problems (e.g., flow uniformity, mixing efficiency, shear minimization).
• Support prototype design by generating computational insights and communicating design recommendations to fluidics , additive manufacturing , advanced materials , and sensor/optical engineering teams.
• Develop reduced‑order models or surrogate models to accelerate design iteration cycles.
• Partner with cross‑functional teams—including fluidics , additive manufacturing , advanced materials , and sensor/optical engineering —to integrate simulation outcomes into product concepts.
• Analyze results, document modeling approaches, and report progress weekly.
• Engage in literature and technology scouting to identify novel computational methods and bioprocessing innovations relevant to Corporate Research.

Benefits

• Personal and Professional Development: Mentoring, leadership programs, internal seminar offerings
• Making an Impact Right from the Start: Comprehensive onboarding, including a virtual online platform
• Welcoming Culture: Mutual support, team spirit and international collaboration; communities on numerous topics such as “Coaching”, “Agile Working” and a “Businesswomen’s Network”
• Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.

What This Job Offers

• Career Level: Intern