In Vivo Research Assistant

START Center for Cancer ResearchSan Antonio, TX
12d

About The Position

XenoSTART, the preclinical division of START is a translational research organization focused on creating relevant preclinical cancer models. Our xenograft models represent each cancer type and disease stage and are established from patients at our domestic and international cancer centers. The XenoSTART Patient-Derived Xenograft (XPDX) platform includes over 2,500 models annotated with each donor patient’s cancer treatment and outcome data and characterized using IHC, DNA/RNA sequencing, and relevant in vivo drug efficacy. Our XPDX models are clinically annotated and include patient treatment history and outcome and are characterized through genomic profiling, histologic analysis, and in vivo drug sensitivity to relevant standards of care. These models may be utilized in the following manner: In vivo PK/PD and efficacy studies In vivo efficacy panel screens (indication or target focused) In licensing of models for internal studies Custom model development Orthotopic and radiotherapy studies Ex vivo and organoid studies W e are hiring a motivated In Vivo Research Assistant. Under direct supervision of the supervisor, this position involves collection of data obtained from industry sponsored and investigator-initiated studies. In addition, this position entails all procedures involved with small animal handling, husbandry, surgery, drug preparation and dosing and other related duties for the START Preclinical Group.

Requirements

  • High school diploma/GED.
  • Minimum of 1 year of similar experience.
  • Must be familiar with Microsoft Office applications.
  • Attention to detail.
  • Ability to work in a fast-paced team environment.

Nice To Haves

  • Bachelor’s degree.
  • Knowledge and training in animal handling and research.

Responsibilities

  • Collect internally generated data including small animal body weights and tumor dimensions using mechanical and electronic devices and stores on internal server.
  • Perform day-to-day procedures including but not limited to small animal handling, husbandry, surgery, anesthesia, cell culture, blood and tissue collection and processing, tumor implantation, cell injection, euthanasia, sample processing including cryopreservation, cryofreezing and fixation, sterilization, maintenance and cleaning. These operations may involve multi-tasking, lifting of greater than forty pounds, standing or sitting for long periods of time and repetitive procedures.
  • Prepare, aliquot and properly store vehicles, drugs, media and other laboratory solutions.
  • Administer agents by various routes on various dosing schedules.
  • Attend regular meetings and briefings regarding preclinical studies as required.
  • Assist in animal and laboratory activities as needed.
  • Assist in data preparation and administrative log management as needed.
  • Follow all Standard Operating Procedures (SOPs).

Benefits

  • Comprehensive health coverage: Medical, dental, and vision insurance provided
  • Robust retirement planning: 401(k) plan available with employer matching
  • Financial security: Life and disability insurance for added protection
  • Flexible financial options: Health savings and flexible spending accounts offered
  • Well-being and work-life balance: Paid time off, flexible schedule, and remote work choices provided
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