Human Resources Business Partner Senior Director (Cell & Genetic Research Site)

Vertex Inc. • Boston, MA

23h • Hybrid

About The Position

We are seeking a strategic, influential, and visionary HR Business Partner Senior Director to lead talent strategies for Vertex’s Cell & Genetic Therapies Research site and Research organizations during a transformative era of scientific innovation and organizational growth. This role will serve as a trusted advisor to Research Senior Vice Presidents and Vice Presidents and their leadership teams, shaping organizational design, culture, and workforce strategies that enable cutting-edge discovery and long-term scientific success. Reporting to the Lead HRBP for the Chief Scientific and Global Research organization, this individual will sit on Research leadership teams and play a critical role in driving enterprise-wide HR initiatives and change leadership. As the primary site HRBP for the Jeffrey Leiden Center for Biologics, Cell & Genetic therapies, the Senior Director will provide and ensure the delivery of HR programs and services including leader coaching and consultation, talent development and succession planning, talent acquisition of key positions, employee experience and engagement, and compensation processes.

Requirements

• Bachelor’s degree in Human Resources or related discipline, or equivalent professional experience.
• Typically requires 12+ years of progressive HR experience, including significant leadership responsibility and experience in complex, multi-site scientific organizations.
• Demonstrated success in leading through subordinate managers and influencing sub-function strategy.
• Recognized expert in HR strategy and organizational effectiveness, with proven ability to influence senior executives and shape sub-functional priorities.
• Deep understanding of scientific environments, including cell and gene therapy, and workforce capability needs for discovery and translational research.
• Advanced proficiency in change leadership, culture transformation, and strategic workforce planning.
• Strong business acumen and ability to translate HR strategies into measurable business outcomes.
• Exceptional communication and influencing skills; ability to negotiate and shape opinions of senior leaders.
• Expertise in leveraging data-driven insights and storytelling to inform decisions and drive transformation.

Responsibilities

• Lead strategic HR initiatives across multiple Research domains (Discovery Biology, Chemistry, Translational Research, Computational Sciences) and influence cross-functional areas such as Data Science and Platform Technologies.
• Serve as a key architect of organizational design and transformation, advising senior leaders on complex change management and culture evolution strategies.
• Drive enterprise-level workforce planning, including capability mapping, succession planning, and talent acquisition strategies aligned with Vertex’s long-range scientific roadmap.
• Leverage advanced analytics and insights to inform strategic decisions, challenge assumptions, and demonstrate measurable impact on scientific and organizational outcomes.
• Influence and shape HR strategy at the sub-function level, ensuring alignment with corporate priorities and Research objectives.
• Build and maintain deep partnerships with HR Centers of Excellence (Total Rewards, Talent Management, People Experience, Strategic Analytics).
• Represent HR on Research leadership forums, contributing to strategic planning and decision-making for the sub-function.
• Ensure flawless execution of critical HR processes (performance management, compensation planning, leadership development) while driving continuous improvement and innovation.

Benefits

• This role is eligible for an annual bonus and annual equity awards.
• Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
• At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
• From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 1,001-5,000 employees