Global Senior Medical Director – Respiratory Pipeline Medical Lead (MD, Sr. Director)

Pfizer • New York, NY

19h • Hybrid

About The Position

The Global Senior Medical Director will be the strategic external scientific face and internal point person of Pfizer's Respiratory pipeline portfolio globally. This role involves advocating Pfizer I&I as a preferred development partner, supporting the operational execution of key studies, and synthesizing insights into actionable intelligence to shape clinical development plans. The goal is to maximize the potential of early pipeline molecules in the respiratory field, support future launches, accelerate tailored life cycle management data generation, and meet the unmet needs of a diverse patient population. The successful candidate will possess a high level of scientific and technical expertise in pulmonology and/or allergy, coupled with an established network of international Key Opinion Leaders (KOLs) to lead medical affairs in this ambition. A key responsibility is defining the medical strategy for the Respiratory Pipeline in close collaboration with clinical development, CSI, International and US stakeholders, and various cross-functional partners. This position requires strong collaboration across functions, creativity, solution-orientation, and leadership skills, with a strong ability to prioritize and focus strategies based on specific asset requirements. These strategies will support Pfizer's vision to be a highly trusted partner providing breakthroughs to customers. The successful candidate will be a core Global Medicine Team member for multiple priority pipeline molecules, an integral member of the Global Medical Respiratory community, and a Respiratory DAWG member. They will partner effectively with International and US cross-functional stakeholders, commercial, PHI, GPD, and corporate affairs for strong alignment and an integrated approach to the Pipeline Strategy. This role is responsible for shaping and executing the medical strategy for the Respiratory pipeline portfolio, ensuring scientific leadership, evidence generation, and stakeholder engagement to support the successful development and launch of innovative therapies in Respiratory.

Requirements

• MD degree.
• Subject matter expertise in Asthma, COPD, and emerging pulmonology indications.
• Comfort operating in mechanism‑driven, cross‑indication strategies, especially early phase.
• Minimum 5+ years of experience in Medical Affairs or Clinical Development.
• Above country experience (global or international).
• Proven track record in pipeline strategy, evidence generation, and external engagement.
• Strong understanding of global regulatory and compliance frameworks.
• Ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
• Proven track record on critical clinical decision making, commercial and regulatory implications of clinical study design elements, analysis of complex scientific data.
• Proven track record of ability to work and partner successfully with cross-functional colleagues in a matrix team setting across countries and internationally with diverse colleagues and cultures.
• Excellent communication, leadership, and matrix management skills.
• Strategic thinking and scientific acumen.
• Ability to influence and lead in a complex, global environment.
• Strong collaboration and stakeholder management skills.
• Passion for innovation and improving patient outcomes.

Nice To Haves

• Board certification/Specialization in Pulmonology or Allergy.
• Experience preferably in Respiratory or immunology (for the 5+ years experience).

Responsibilities

• Develop and implement the global medical affairs strategy for Respiratory pipeline assets, aligned with overall business objectives.
• Provide scientific and clinical expertise to inform development plans and lifecycle management in collaboration with cross functional colleagues to develop perspectives on future treatment landscapes, unmet needs, epidemiology of disease conditions and biomarkers for prioritized programs.
• Partner with early commercial development to deliver the target product profile (TPP) and medical differentiation index assessment.
• Work closely with Business development on due diligence for potential external opportunities.
• Support the phase II and III respiratory clinical trials education and awareness.
• Be accountable for uplifting respiratory scientific capability across Medical Affairs, including internal education in close collaboration with US and International leads.
• Engage in thought partnership with non‑respiratory colleagues.
• Help establish Respiratory as a credible pillar alongside Derm.
• Define and oversee the integrated evidence plan including clinical trials, real-world evidence, and investigator-initiated studies for Respiratory/allergy pipeline.
• Lead collaborative research partnerships and strategy for independent Pfizer sponsored research.
• Ensure robust data dissemination through publications, congress presentations, and scientific exchange in collaboration with the R&D team and the publication lead.
• Build and maintain relationships with key external experts, professional societies, and patient advocacy groups.
• Lead and implement globally insight generation activities, understanding the external customer perspectives through peer-to-peer interactions, data/facts/observations from field medical and advisory board meetings.
• Lead and develop data interpretation and alignment activities with internal and external partners to inform decision making and to support development of educational activities, medical strategies and tactics.
• Attend Respiratory & allergy medical congresses, interact with key investigators and review literature, focusing on emerging data in MOAs relevant to our early development portfolio and provide insights to inform on the development strategy.
• Be responsible for future creation of the respiratory team in accordance to the respiratory portfolio evolution as well as for making strategic resourcing decisions.
• Partner with Clinical Development, Regulatory, and Commercial teams to ensure alignment on scientific messaging and launch readiness.
• Support development and execution of internal medical training curriculum around asset data and relevant disease area content in collaboration with the Medical Content and Communication team.
• Partner with the dermatology pipeline lead to ensure a unified and aligned scientific narrative for assets that have multiple indications across Dermatology and Respiratory conditions (e.g. AD and Asthma).
• Work closely with the International and the US leads to ensure alignment of the respiratory strategy with the insights collected as well as with the regional and countries needs.
• Maintain high ethical standards in all scientific communications.

Benefits

• 401(k) plan with Pfizer Matching Contributions.
• Additional Pfizer Retirement Savings Contribution.
• Paid vacation.
• Holiday and personal days.
• Paid caregiver/parental and medical leave.
• Health benefits to include medical, prescription drug, dental and vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees