Global Commercial Director, ImmunoOncology

AstraZeneca • Gaithersburg, MD

1d • $231,989 - $347,983 • Hybrid

About The Position

As Global Commercial Director, ImmunoOncology, this role shapes how ground-breaking oncology medicines reach patients worldwide. Working across a broad and innovative pipeline, the position blends commercial competence with scientific understanding to bring novel treatments to those who need them most. It leads the commercial strategy for key immuno-oncology disease areas, with a particular focus on the end-to-end launch and sustained performance of the MATTERHORN gastric cancer programme. Operating at the centre of cross-functional collaboration, this role drives focused execution, informed decision-making and ambitious, insight-led choices that influence outcomes for patients, markets and the business. Ready to challenge convention, test new ideas and guide a high-performing team to deliver impact at scale?

Requirements

• Strong strategic thinking, judgment, and influencing skills to lead across regions and markets with clear financial accountability.
• Demonstrated experience owning or leading significant global commercial budgets, including investment prioritization, phasing, and governance.
• Confirmed ability to use performance and financial analytics to inform decision making and drive course corrections.
• Bachelor’s degree required; preferably a business or scientific graduate degree with a business related postgraduate qualification.
• Postgraduate degree in biological, chemical, or pharmacological sciences strongly desired.
• 10+ years’ experience in the pharmaceutical industry, including at least 5 years in oncology/immuno-oncology marketing, strategy, or life sciences consulting.
• Strong leadership capabilities to set direction, inspire commitment, balance short and longterm financial and strategic needs, and resolve complex issues.
• Strong business acumen and complex problem solving skills.
• Experience developing and delivering short and longterm strategic plans for oncology portfolios, including postlaunch performance and budget management.

Nice To Haves

• Postgraduate degree in biological, chemical, or pharmacological sciences strongly desired.

Responsibilities

• Lead the creation, execution and continuous refinement of a long-term commercial vision and strategy for immuno-oncology disease area(s), ensuring robust lifecycle management from prelaunch through postlaunch.
• Chair and direct the IO disease area(s) Global Brand Team (GBT), setting clear priorities, driving accountability and ensuring coordinated delivery across functions and phases of launch.
• Hold global budget accountability for the disease area, including development of the annual operating plan, budget phasing, investment prioritisation
• Own global commercial leadership of the MATTERHORN gastric cancer launch, ensuring launch excellence, sustained performance and delivery against strategic and financial objectives.
• Lead all aspects of postlaunch performance by monitoring uptake, driven dynamics, access and executional efficiency, initiating data-driven course corrections and reallocating resources where needed.
• Represent and articulate the commercial and marketing strategic vision for the disease area(s) within the Global Portfolio Team (GPT), influencing key decisions and trade-offs.
• Partner closely with the Global Medicines Lead (GML) to align commercial and medical strategies, ensuring integrated planning and coordinated resource deployment.
• Develop and implement commercial strategies that optimise revenue, volume, margin and access across geographies within agreed budget envelopes.
• Engage regional and key market stakeholders to drive launch readiness, build capabilities and ensure effective deployment of global and local budgets.
• Act as indication lead in senior forums, communicating commercial performance, financial outlooks and investment trade-offs to senior executives and governance committees.
• Deliver Phase 3 and prelaunch marketing strategies that set up successful launches and maintain strong postlaunch momentum.
• Collaborate with extended teams to develop and implement sustainable pricing and access strategies across multiple indications.
• Lead the development and global implementation of brand strategy, positioning, launch plans, forecasts, critical metrics and ongoing financial and performance analytics for the disease area(s).

Benefits

• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 5,001-10,000 employees