Genomics Clinical Variant Analyst II - Next Generation Seq

Nationwide Children's Hospital • Columbus, OH

1d

About The Position

Overview: Job Description Summary: Accurately identifies, classifies, and documents variants following practice guidelines under the direction of the Laboratory Directors and Variant Scientists. Assists with the day-to-day operations of variant assessment, curation, and documentation to accurately identify and classify genomic alterations detected through genomic testing and translational studies. Job Description: Essential Functions: Analyzes and interprets genomic data to identify genetic variants and their potential clinical significance. Maintains ongoing knowledge of current theories and principals of human medical genetics, cancer genetics and hereditary cancer disorders. Utilizes various bioinformatics tools and databases to perform variant annotation and classification. Collaborates with other members of the clinical team to review and interpret genomic findings. Prepares detailed clinical reports summarizing genomic findings and their implications for patient care. Participates in quality control and quality assurance activities to ensure accuracy and consistency of genomic data analysis. Stays up-to-date with the latest developments in genomics and bioinformatics, and applies this knowledge to improve variant analysis workflows and methodologies.

Requirements

• Bachelor's Degree in molecular genetics, human genetics, genetic counseling, molecular pathology, or computational field, required.
• Moderate knowledge of principles of variant interpretation and analysis, including Human Genome Variation Society nomenclature.
• Moderate familiarity with bioinformatic processes and concepts such as variant discovery, including a knowledge of some genomic software including genome browsers and human variant databases.
• Strong analytical skills, attention to detail, and the ability to critically read and interpret data independently from scientific publications.
• Ability to perform advanced technical writing, as well as excellent communication and computer skills.
• Good organizational and interpersonal skills.
• Ability to initiate and work on several projects at a time with minimal supervision; motivation to follow through to completion while adhering to deadlines and maintaining accurate records.
• Five years of experience in Laboratory Genetics, Cancer Genomics, Computational biology or a related field, required.

Nice To Haves

• Experience in variant analysis, preferred.

Responsibilities

• Analyzes and interprets genomic data to identify genetic variants and their potential clinical significance.
• Maintains ongoing knowledge of current theories and principals of human medical genetics, cancer genetics and hereditary cancer disorders.
• Utilizes various bioinformatics tools and databases to perform variant annotation and classification.
• Collaborates with other members of the clinical team to review and interpret genomic findings.
• Prepares detailed clinical reports summarizing genomic findings and their implications for patient care.
• Participates in quality control and quality assurance activities to ensure accuracy and consistency of genomic data analysis.
• Stays up-to-date with the latest developments in genomics and bioinformatics, and applies this knowledge to improve variant analysis workflows and methodologies.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees