Founding Software Engineer (Genomics Platform)

TalencoreBoston, MA
10d$220,000 - $250,000Hybrid

About The Position

Our client, a biotech startup in Boston, Massachusetts, is seeking a highly skilled engineer to develop and maintain a genomic diagnostics platform, transforming raw genomic and scientific datasets into clinically actionable insights. The role involves backend development, workflow orchestration, and cloud infrastructure, with a strong emphasis on scientific computing and analytical pipelines. The ideal candidate will collaborate closely with scientists, bioinformaticians, and cross-functional teams to build scalable, production-ready pipelines in a regulated, clinical environment.

Requirements

  • 7-10+ years of software engineering experience in life sciences, diagnostics, scientific computing, or genomics.
  • 6+ years of professional software engineering experience with a focus on scientific computing, analytical pipelines, HPC-style workflows, or large-scale data ingestion systems.
  • Demonstrated ability to lead or own pipeline and workflow architecture in production environments.
  • Expertise with large scientific or genomic datasets, including ingestion, transformation, validation, and distributed processing.
  • Experience processing raw scientific data such as genomic reads, image data, or sensor data.
  • Deep experience with workflow orchestration (WDL, Cromwell, Nextflow, Airflow, or equivalent).
  • Proven background building cloud-based backend systems in GCP, supporting large volumes of sequential data processing.
  • Experience with GCP Batch or distributed compute frameworks.
  • Experience with containerization and reproducibility (Docker, containerized scientific pipelines).
  • Strong understanding of PHI handling, data privacy, and compliance within scientific or clinical environments.
  • Ability to work closely with scientists, bioinformaticians, and cross-functional teams to convert complex analytical requirements into scalable engineering solutions.
  • Familiarity with scientific computing libraries (PyTorch, NumPy, Pandas, statistical modeling).
  • Expertise in monitoring scientific workloads at scale (Prometheus, Grafana, or equivalent).

Responsibilities

  • Develop and maintain a genomic diagnostics platform and associated backend systems.
  • Lead or own pipeline and workflow architecture in production environments.
  • Design, implement, and optimize analytical pipelines for large-scale scientific or genomic datasets, including ingestion, transformation, validation, and distributed processing.
  • Work with workflow orchestration tools such as WDL, Cromwell, Nextflow, Airflow, or equivalents.
  • Build cloud-based backend systems, ideally on GCP, capable of handling large volumes of sequential data processing.
  • Ensure containerization and reproducibility of pipelines using Docker or other container technologies.
  • Maintain strong PHI handling, data privacy, and compliance practices in scientific or clinical environments.
  • Collaborate with cross-functional teams to translate complex analytical requirements into scalable engineering solutions.
  • Focus on scientific computing, HPC-style workflows, and large-scale data ingestion systems.

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

No Education Listed

Number of Employees

1-10 employees

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