Fall Co-op/Bioanalytical DMPK
About The Position
The GSK Drug Metabolism and Pharmacokinetics (DMPK) organization is responsible for the delivery of key DMPK support (in vitro, pharmacokinetic, and bioanalytical) that helps drive early drug discovery programs. Within that structure, the Bioanalytical team is responsible for the quantitation of drug and drug related molecules in samples generated both in vitro and in vivo. Additionally, a key remit of the U.S. DMPK organization is the modernization and optimization of processes to allow for increased throughput and efficiency. A pivotal aspect of that remit is the expansion of DMPK assays by implementing new bioanalytical approaches. The support of these assays presents an opportunity for a student to learn and contribute via sample preparation, LC-MS/MS and SPE-MS/MS analysis, and data interpretation and tracking. The GSK Drug Metabolism and Pharmacokinetics group is seeking a highly motivated individual to join our Bioanalytical team for a 6 to 12-month internship. The successful candidate’s primary responsibility will be assisting in the analysis of DMPK screening assays using both LC-MS/MS and high throughput SPE-MS/MS platforms. Through working closely with Bioanalytical team members the candidate will learn key concepts of mass spectrometry analyses, including sample preparation, instrument/data analysis software, and data interpretation. Additionally, a high achieving candidate will have opportunities to evaluate related analytical methodologies in an effort to optimize workflows. The ability to work both independently and within a team environment is expected.
Requirements
- Pursuing a degree in Biology, Chemistry, Biomedical Engineering, or similar discipline
- Must be able to work full-time (35-40 hours/week) throughout the duration of the 6 month co-op (September 2026 ~ March 2027)
- Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program
- Post-doctoral candidates are not eligible
- Must successfully pass a drug screen and background check prior to assignment target start date
- Successfully pass our immersive GSK Digital Assessment
Nice To Haves
- Experience with pipetting and track record of good laboratory practices
- Basic understanding of Drug Metabolism, Pharmacokinetic, or Bioanalytical principles
- Organic and/or analytical chemistry
- Liquid chromatography
- Mass Spectrometry
Responsibilities
- Assisting in the analysis of DMPK screening assays using both LC-MS/MS and high throughput SPE-MS/MS platforms
- Learn the basic principles of qualitative LC-MS/MS and SPE-MS/MS through the analysis of in vitro DMPK assay samples
- Analyze, interpret, and present data to DMPK staff
- Help with the implementation and assessment of new methodologies for sample analysis
- Assist in troubleshooting and optimizing workflows based on experiences during instrument use and data analysis
Benefits
- Relocation stipend for candidates hired for an on-site role or hybrid role, and reside outside of 50-miles from their assigned work location
- Competitive hourly pay rate
- Benefits (eligibility determined the month following date of hire)
- Overtime pay, in accordance with federal and state requirement
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
5,001-10,000 employees
