Expert Pharma Biophysical Scientist

Cogent Scientific•Louisville, CO

About The Position

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to build lasting partnerships that enable the life sciences industry to accelerate discovery and innovation in research and manufacturing. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation. Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. We aim to recruit the best people who stand out among their peers and embody our Core Values: C lient Focused: We only succeed when our clients succeed. O utstanding: We deliver meticulous results through outstanding performance. G ood: We act ethically and morally. E mployee-Centric: We honor and support our employees. N imble: We are prepared to adapt in an ever-changing industry. T eam-Oriented: We collaborate with each other and with our clients. We currently have a role available for an Expert Pharma Biophysical Scientist. Job duties include, but are not limited to: Characterizing protein-ligand and protein-protein interactions by a variety of methods including, but not limited to the following: Intact protein mass spectrometry, fluorescence spectroscopy, SPR (SPR experience required). Biophysically characterizing protein samples destined for multiple workflows. Using proprietary biophysical tools to interrogate protein ligand interactions to triage or advance compound series. Developing assays and utilizing SPR (e.g. Biacore 8K or similar models to routinely determine binding kinetics. Designing and obtaining SPR-based mechanism of action studies to characterize binders. Executing SPR to drive Structure-Activity Relationship (SAR) and target potency. Exposure to Biacore 8K or 1S systems preferred. Job requirements include, but are not limited to: MS in Biochemistry, Chemistry or related field with 3-5 years of pharma laboratory experience outside of academia. PhD with 0-3 years of industrial lab/post-doc experience will also be considered. Thorough understanding of the theory of above-mentioned techniques. Excellent communication skills – verbal and written. Works well both within a team and as an individual. Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery. This is a day shift position (approx. 8a-5p local time). Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic. Additionally, if you require a reasonable accommodation during the application or interview process, please let us know. This job posting will close by 6/1/2026 or when a candidate is identified, whichever comes first.

Requirements

MS in Biochemistry, Chemistry or related field with 3-5 years of pharma laboratory experience outside of academia. PhD with 0-3 years of industrial lab/post-doc experience will also be considered
Thorough understanding of the theory of above-mentioned techniques
Excellent communication skills – verbal and written
Works well both within a team and as an individual
Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions

Nice To Haves

Exposure to Biacore 8K or 1S systems preferred
The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery

Responsibilities

Characterizing protein-ligand and protein-protein interactions by a variety of methods including, but not limited to the following: Intact protein mass spectrometry, fluorescence spectroscopy, SPR (SPR experience required)
Biophysically characterizing protein samples destined for multiple workflows
Using proprietary biophysical tools to interrogate protein ligand interactions to triage or advance compound series
Developing assays and utilizing SPR (e.g. Biacore 8K or similar models to routinely determine binding kinetics
Designing and obtaining SPR-based mechanism of action studies to characterize binders
Executing SPR to drive Structure-Activity Relationship (SAR) and target potency