Enterprise Programs - Senior Program Manager

Amgen • Thousand Oaks, CA

1d • Hybrid

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, you are part of something bigger, driven by the shared mission to serve patients living with serious illnesses. Since 1980, Amgen has pioneered biotech in the fight against tough diseases, focusing on Oncology, Inflammation, General Medicine, and Rare Disease, reaching millions of patients annually. As a member of the Amgen team, you will contribute to making a lasting impact by researching, manufacturing, and delivering innovative medicines. The culture is collaborative, innovative, and science-based, offering a thriving environment for those passionate about challenges. In this vital role, you will lead strategic, business-driven technology initiatives that deliver measurable outcomes and business value. This position is suited for a seasoned program leader with a strong understanding of both business processes and enterprise technology. You will oversee a portfolio of transformational initiatives aimed at enabling innovation, improving operational efficiency, and advancing data-driven decision making. Working in a global, matrixed environment, you will collaborate closely with cross-functional partners across business units, technology functions, and external partners. A key focus is aligning technology delivery with business priorities, ensuring every program contributes to tangible, strategic outcomes. Success in this role requires a proven ability to translate vision into execution, manage change, and influence cross-functional stakeholders at all organizational levels.

Requirements

• Doctorate degree and 2 years of Scientific and/or IT Operations and/or Business experience
• Master’s degree and 4 years of Scientific and/or IT Operations and/or Business experience
• Bachelor’s degree and 6 years of Scientific and/or IT Operations and/or Business experience
• Associate’s degree and 10 years of Scientific and/or IT Operations and/or Business experience
• High school diploma / GED and 12 years of Scientific and/or IT Operations and/or Business experience

Nice To Haves

• 6–10 years of experience delivering business technology solutions and programs in a matrixed, global organization
• Demonstrated success in aligning technology execution with business strategy to achieve measurable outcomes
• Experience leading transformational programs or M&As
• Experience leading programs involving business process optimization, digital product rollouts, enterprise applications, or analytics platforms
• Proficiency with program and portfolio management tools (e.g., Smartsheet, JIRA, ServiceNow, Confluence) and executive reporting dashboards.
• Strong stakeholder engagement, communication, and change leadership skills across business and technical audiences
• Ability to manage vendor relationships and third-party service providers in a co-delivery model.
• Familiarity with data privacy, GxP, and regulatory compliance frameworks in a life sciences context
• PMP, SAFe, Agile, or Lean certification preferred!

Responsibilities

• Lead delivery of complex programs that align to enterprise goals and deliver measurable value!
• Drive transformational programs to deliver on business priorities
• Work closely with business stakeholders to define outcomes, ensure solutions are implemented as planned and drive adoption
• Translate business needs into executable program plans, including scope, timelines, resource planning, and budget oversight
• Partner with cross-functional teams including data & analytics, enterprise applications, and digital product teams to deliver outcomes
• Manage program governance, steering committees, and status reporting for senior partners
• Drive structured methodologies such as Agile, SAFe, or hybrid approaches to improve delivery efficiency and responsiveness
• Track program KPIs, ROI, and performance metrics aligned to business success criteria
• Coordinate organizational change, business readiness, and stakeholder engagement activities across functions and geographies
• Build trust and alignment across technology teams and business leaders to sustain long-term strategic partnerships
• Apply continuous improvement practices to program execution and delivery frameworks.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

What This Job Offers

• Job Type: Full-time
• Career Level: Senior