Engineer Senior, Synthetic Kilo Laboratory and Analytical Chemistry Support - (JP14942)
About The Position
3 Key Consulting is hiring an E ngineer Senior, Synthetic Kilo Laboratory and Analytical Chemistry Support for a consulting engagement with our direct client, a leading global biopharmaceutical company. Job Description: The ideal candidate holds a bachelor’s degree with four years of relevant industry experience, a master’s degree with two years of experience, or a PhD in Chemical Engineering, Chemistry, or a related discipline, with experience supporting small-molecule API drug substance development. This role reports to the Associate Director of Engineering and provides on-site laboratory support and scientific contribution. The candidate will work in a highly collaborative, team-based environment alongside process development of chemists, chemical engineers, and analytical scientists. The role also interfaces with Environmental, Health, Safety & Sustainability (EHSS), Facilities & Engineering, laboratory management, and external vendors. This is a laboratory-focused position requiring strong technical aptitude, curiosity, and motivation to advance synthetic laboratory operations, automation, and data-driven experimentation. The successful candidate will be capable of working independently on defined objectives while contributing effectively within a fast-paced, cross-functional team. Why is the Position Open? Supplement additional workload on team
Requirements
- Hands-on execution and support of synthetic chemistry experiments, kilo-lab operations, equipment use, and EHSS-compliant laboratory practices.
- Design, execution, and interpretation of HTE workflows for reaction, solubility, and crystallization screening, including use of automation and data-driven experimentation.
- Application of analytical and solid-state tools (HPLC, XRPD, DSC/TGA) alongside kinetic modeling and PAT awareness to translate experimental data into process understanding.
- Doctorate degree OR Masters degree and 2 years of experience OR Bachelors degree and 4 years of experience OR Associates degree and 8 years of experience OR High school diploma / GED and 10 years of experience
- The candidate should demonstrate a solid foundation in chemical synthesis, synthetic laboratory operations, and scale-relevant safety practices.
- Strong written, verbal, and presentation skills are required.
Nice To Haves
- Experience with high-throughput experimentation (HTE) for reaction screening, solubility assessment, and crystallization screening is desirable.
- Familiarity with automated HTE workflows and solid-state characterization techniques is a plus.
- Hands-on experience with analytical tools such as HPLC, XRPD, and thermal analysis (DSC/TGA) is advantageous.
- Exposure to kinetic modeling platforms and process analytical technology (PAT) tools is preferred.
- Proficiency with standard office software (Microsoft Word, Excel, PowerPoint, and Outlook) is required.
- Experience with Dynochem or similar process modeling and simulation tools is a plus.
Responsibilities
- Support day-to-day operations of the Synthetics Lab through hands-on experimental execution and technical support.
- Operate lab equipment and accessories in compliance with safety and operational procedures; develop increasing proficiency as a lab superuser.
- Execute synthetic experiments with minimal supervision and escalate technical or safety concerns as appropriate.
- Collaborate with process development of chemists and engineers to generate, interpret, and document experimental data.
- Contribute to cross-functional project teams by delivering experimental results aligned with project timelines and objectives.
- Author and support review of technical documentation, including process descriptions, batch records, SOPs, and safety documentation.
- Review various documentation and mine data using statistical tools.
- Design and execute high-throughput experimentation (HTE) studies for reaction screening and solubility/crystallization screening under project guidance.
- Support development and operation of automated HTE workflows to enable efficient and reproducible experimentation.
- Execute solubility and crystallization of screening experiments and assist in interpretation of results to inform process development decisions.
- Perform solid-state and analytical characterization using techniques such as HPLC, XRPD, DSC/TGA, and related methods.
- Document, analyze, and communicate HTE and solid-state data to project teams.
- Support the use of kinetic modeling platforms and PAT tools for process understanding and optimization.
- Assist with equipment scheduling and coordination to support experimental demands.
- Support routine equipment maintenance, troubleshooting, and preventative maintenance activities.
- Operate and support maintenance of lab equipment and utilities, including reactors, filtration systems, heat transfer units, and chillers.
- Assist with laboratory inventory management, including monitoring usage, ordering consumables, and restocking supplies.
- Follow established procedures for equipment handling, maintenance, and repair, escalating complex issues as needed.
- Participate in laboratory improvement initiatives, including equipment upgrades, workflow optimization, and automation efforts.
- Support development and maintenance of training materials for lab operations and equipment.
- Complete required training and support training compliance through the client training system.
- Participate in core team meetings and contribute experimental data and technical updates.
- Support EHSS risk assessments, safety reviews, and implementation of mitigation actions under guidance from senior staff.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
