Engineer III

Takeda•Lexington, MA

3d•$104,000 - $168,000•Hybrid

About The Position

Takeda Development Center Americas, Inc. is seeking an Engineer III with the following duties: Independently carryout bioreactor operations across various scales, ranging from 250ml to 10 L bioreactors; Prepare experimental protocols, and support tech transfer of developed cell culture process to pilot team and manufacturing facility; Design experiments, interpret the data independently, identify complex technical issues and implement solutions under supervision; Contribute to technical reports through writing and consolidating technical documents; Actively participate and interact with support process development, optimization, characterization, troubleshooting problems, supporting large scale studies, and supporting project goals; Support technology transfer through writing and consolidating technical documents, reviewing batch records, coordinate within department as well as cross functionally with peers on projects; Contribute to evaluation of new technology/equipment that can be applied across multiple programs; Document data accurately as per established company guidelines and procedures; Draft technical reports, memos, procedures, protocols, and presentations, provide organizational support and cross-functional project team participation and present to department and at project team meetings; Execute bioreactor operations, clarifications, and purification using high throughput systems such as ambr250 and Tecan; Up to 20% remote work allowed.

Requirements

Master’s degree in Chemistry, Biology, Pharmacy, Engineering, or related Pharmaceutical Science.
Execute bioreactor operations, primary clarification, and purification using high-throughput systems (e.g., ambr250, Tecan), and design experiments to assess and optimize process performance
Independently interpret experimental data, identify complex technical issues, and implement solutions under supervision.
Contribute to the evaluation and integration of new technologies and equipment across multiple programs
Collaborate with cross-functional teams to support the tech transfer of processes to Pilot, Manufacturing, and external CDMOs, ensuring seamless integration of new processes and technologies
Author and revise technical documents, including SOPs and process development reports
Provide cross-training for team members on various analytical instruments and techniques
Conduct product quality testing using tools such as Solo-VPE, Lunatic, HPLC, UPLC, and UV spectrophotometer.

Responsibilities

Independently carryout bioreactor operations across various scales, ranging from 250ml to 10 L bioreactors
Prepare experimental protocols, and support tech transfer of developed cell culture process to pilot team and manufacturing facility
Design experiments, interpret the data independently, identify complex technical issues and implement solutions under supervision
Contribute to technical reports through writing and consolidating technical documents
Actively participate and interact with support process development, optimization, characterization, troubleshooting problems, supporting large scale studies, and supporting project goals
Support technology transfer through writing and consolidating technical documents, reviewing batch records, coordinate within department as well as cross functionally with peers on projects
Contribute to evaluation of new technology/equipment that can be applied across multiple programs
Document data accurately as per established company guidelines and procedures
Draft technical reports, memos, procedures, protocols, and presentations, provide organizational support and cross-functional project team participation and present to department and at project team meetings
Execute bioreactor operations, clarifications, and purification using high throughput systems such as ambr250 and Tecan