Drug Metabolism Pharmacokinetics (DMPK) - LC-MS Intern
About The Position
The Drug Metabolism and Pharmacokinetics (DMPK) department plays a key role in Arcus' R&D by characterizing the ADME properties of drug candidates and providing data-driven insights to drug discovery and development. Two summer internship positions in DMPK are available for this year. This internship offers hands-on experience in small molecule bioanalysis and data processing. Interns will assist in developing high-throughput LC-MS methods for plasma protein binding (PPB) assays and building workflows for metabolite identification (MetID) data analysis using Compound Discoverer.
Requirements
- Complete or enroll in a Master's or PhD program in Pharmaceutical Sciences, Analytical Chemistry or a related field.
- Basic wet-lab experience is required
- Excellent written and verbal communication skills
- Ability to learn quickly and work in a team environment
- All applicants must be actively enrolled in an accredited academic program for Fall 2026.
Nice To Haves
- Hands-on experiences in LC-MS are preferred
- Prior internship or research experience in DMPK or related fields is a plus
Responsibilities
- Develop and optimize high-throughput LC-MS methods using serum albumin columns to evaluate compound plasma protein binding in human and preclinical species.
- Assist in building MetID data analysis workflow using Compound Discoverer software.
- Perform routine lab activities including sample preparation, data collection and analysis.
- Maintain accurate experimental records.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
501-1,000 employees
