Director, People Operations

Alnylam Pharmaceuticals • Cambridge, MA

11h • $191,300 - $258,700 • Hybrid

About The Position

The Director, Regional People Operations will manage the People Operations function, systems and services across the region. This role is accountable for building a high‑performing team, continuously improving processes, and partnering across HR Centers of Excellence to ensure organizational alignment. Reporting to the VP, People Experience, this position plays a critical role in advancing how HR delivers an Efficient, Effective, and Exceptional Experience across the organization!
This is a hybrid position and will primarily be based in Cambridge, MA.

Requirements

• 10+ years of related experience required, with a strong background in human resources, consulting, and/or a comparable field.
• Bachelor’s degree or equivalent required.
• Proven experience building and leading high‑performing teams within complex, matrixed, or global organizations, including leading teams through change.
• Strong systems and process orientation, with demonstrated success driving continuous improvement initiatives.
• Ability to balance standardization with flexibility to meet diverse customer and business needs.
• Demonstrated ability to manage a team is a must.
• Demonstrated change in management skills and drive & influencing skills needed.

Responsibilities

• Lead People Operations transformation initiatives, partnering across HR to evolve systems, processes, and ways of working that collectively enable an Efficient, Effective, and Exceptional Experience.
• Build, develop, and lead a high‑performing People Operations team, establishing clear operating standards, accountabilities, and a culture of continuous improvement.
• Design and continuously enhance employee experiences across the end‑to‑end people lifecycle using a process‑driven, customer‑focused approach.
• Partner closely with HR Business Partners and Centers of Excellence to deliver integrated, enterprise‑aligned solutions.
• Leverage data, analytics, and systems insights to identify gaps, address limitations, and drive measurable operational improvements.
• Drive a strategic approach to the development of People Operations, continuously seeking out best practices and evaluating opportunities for automation where appropriate.
• Act as a trusted advisor across HR functions, ensuring People Operations capabilities enable enterprise priorities and employee experience outcomes.

Benefits

• We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match.
• Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.
• We also offer generous family resources and leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Director