Director Global HEOR, Povetacicept

Vertex Inc.•Boston, MA

7d•Hybrid

About The Position

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group in Boston, MA. The Health Economics & Outcomes Research Director will lead HEOR strategies and execution of evidence generation that optimize the value proposition of Vertex’s povetacicept assets through each stage of development, including launch and post-launch phases. This position reports to the Senior Director Global HEOR Kidney.

Requirements

Provides technical expertise in HEOR and able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices
Strong track record of publications in peer-reviewed journals demonstrating experience in evidence synthesis, patient reported outcomes, observational research, and health economic modeling
Demonstrate capabilities to develop global strategic HEOR plans and execute studies with comprehensive understanding of clinical development strategies and trial designs
Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development plans, to identify evidence gaps and formulate evidence generation strategies
Market Access experience, including direct experience in making submissions to relevant payers and interacting with them is strongly desired (US and EX-US)
Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences
Broad and comprehensive understanding of the legal and regulatory environment of the pharmaceutical industry, demonstrated integrity on work-related compliance considerations and solid ethics
Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline.
Typically requires 10 years of experience in health economics and outcomes research, or directly-related field and industry, or the equivalent combination of education and experience

Responsibilities

Serves as the HEOR povetacicept Lead focusing on pipeline indications: pMN and/or gMG
Develops the HEOR strategy for povetacicept from early development through product lifecycle
Serves as HEOR lead to cross-functional and cross-regional teams to align strategic plans to stakeholder needs and represent the voice of HEOR
Execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value
Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning
Supports the integration of HEOR evidence in health technology appraisal submissions for relevant assets
Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact
Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative
Collaborates closely with global brand marketing, clinical, and other functional teams to support and enhance access to marketed products across various regions and serves as HEOR lead to cross-functional teams
Oversee the design and execution of HEOR studies and apply best practices for HEOR analyses, modeling and dissemination; ensures the highest quality standards for research and dissemination

Benefits

This role is eligible for an annual bonus and annual equity awards.
Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

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