Director, Data Engineering & Management TOQ & ReDev

Alnylam Pharmaceuticals

6d • Hybrid

About The Position

Overview:
The Director, Enterprise Data Architect leads the data engineering and data management capability supporting Alnylam’s Technical Operations & Quality (TOQ) and Research & Development (R&D) organizations. This role owns the design, build, and operation of data platforms and pipelines on the Alnylam Lakehouse (Snowflake), enabling manufacturing, quality, supply chain, clinical, and research analytics in a GxP-regulated environment. Based in Cambridge, MA, the Director partners closely with TOQ/ReDev business leaders and technology counterparts while remaining hands-on with complex data engineering challenges.

Requirements

• Bachelor’s degree in Computer Science, Engineering, Information Systems, or a related field
• 8+ years of experience in data engineering or data platform development, with at least 3 years in a people-leadership role
• Strong hands-on experience with modern data platforms and architectures, including cloud data services and Snowflake-based lakehouse environments
• Experience designing and delivering data integrations in regulated (GxP) environments, with a solid understanding of data integrity and validation principles
• Proven ability to partner with business stakeholders and translate complex requirements into scalable, compliant data solutions

Nice To Haves

• Experience in biotechnology, pharmaceutical, or life sciences organizations
• Familiarity with manufacturing, laboratory, quality, or clinical systems (e.g., MES, LIMS, ELN, QMS, clinical data platforms)
• Experience working within agile or product-oriented delivery models

Responsibilities

• Own delivery of data engineering and data management solutions for TOQ and R&D, ensuring reliable, scalable, and GxP-compliant data platforms that support manufacturing, quality, clinical, and research decision-making
• Architect and implement end-to-end data pipelines and data products on the Alnylam Lakehouse, integrating manufacturing, laboratory, quality, clinical, and research systems using modern data engineering practices
• Lead adoption of modern data movement and integration patterns, transitioning away from legacy batch and point-to-point integrations toward managed ingestion, streaming, and governed data sharing
• Serve as the primary data engineering partner to TOQ/ReDev business and technology leaders, working in an embedded, “two-in-a-box” model to co-design and deliver next-generation capabilities
• Contribute hands-on technical leadership to complex integration, data quality, and performance challenges while setting engineering standards and best practices for the team
• Support evaluation and implementation of new manufacturing and supply chain platforms by defining data integration requirements and ensuring alignment with Alnylam data architecture standards
• Build, lead, and develop a high-performing team of data engineers and data management professionals, with accountability for delivery across full-time and variable resources

Benefits

• comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match
• Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks
• We also offer generous family resources and leave

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Number of Employees: 501-1,000 employees