Co-op: Analytical Development

Prime Medicine • Cambridge, MA

3h • $23 - $33

About The Position

Prime Medicine is seeking a diligent, motivated, and enthusiastic co-op for the Fall 2026 cycle who has interest in state-of-the-art analytical technologies including HPLC, LC-MS, and capillary electrophoresis to join the analytical development (AD) team. The successful candidate will be able to participate in the development of separation-based analytical methods for the Prime Editor delivery platform and work cross-functionally to advance the Prime pipeline. Also, this co-op student will have hands-on opportunities to gain exposure to a broader range of analytical techniques (such as flow cytometry), gaining familiarity with scientific and regulatory requirements for phase-appropriate analytical testing. There will also be valuable opportunities to participate in other cross-functional projects that are crucial to the success of in vivo and ex vivo gene editing therapeutic drug development.

Requirements

• Currently enrolled in a B.S. or M.S. program in biochemistry, chemistry, chemical engineering, pharmaceutical science, or a related field.
• Basic knowledge of separation sciences and technologies.
• Ability to handle multiple projects in a fast-paced environment.
• Excellent troubleshooting and communication skills.
• Ability to work independently and within a team.
• Skilled in documenting findings and activities in comprehensive reports and ensuring proper inventory of materials and analytical equipment.

Nice To Haves

• Hands-on experience with LC-MS, capillary electrophoresis, and/or cell culture is preferred.
• Previous co-op experience in the biotechnology industry.
• Independently motivated, detail-oriented, and excellent problem-solving abilities.

Responsibilities

• Participate in separation-based method (HPLC, LC-MS) development to assess lipid nanoparticle (LNP) drug products and their components. Assist senior-level scientists with buffer preparation, maintenance of instruments, and developing up-to-date analytical methods that help to increase in-process analytics capacity.
• Participate in cell-based method (flow cytometry) development to assess cell therapy drug products. Support the maintenance of instruments.
• Support the phase-appropriate product development (PD) sample analyses, release testing, and stability studies for the characterization and release of cell and gene therapy drug products, drug substances, and critical raw materials.
• Document, present, and communicate experimental data and conclusions in an electronic notebook, following cGMP documentation practices.
• Data analysis, interpretation, and presentation within the team.

Benefits

• A cutting-edge scientific team dedicated to mentorship and networking
• Experience in the field of gene editing and analytical development/early-stage QC
• Participation in regular scientific seminars with industry experts
• Prime Medicine offers a comprehensive Total Rewards package with robust health, financial, and wellness benefits—including medical, dental, vision, life insurance, a 401(k) match, and equity programs—along with generous paid time off, wellness days, and company-wide recharge breaks.

What This Job Offers

• Career Level: Intern