Chromatography Principal Scientist

Sanofi • Cambridge, MA

14d • Onsite

About The Position

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. Sanofi is seeking a highly motivated individual to join our analytical group as a Chromatography Principal Scientist . The group is part of the synthetic platform within Global CMC Development with focus on small molecules that is striving to become an industry leader in the development of transformative medicines. The primary responsibility of this position is to provide analytical support to the chemistry teams and to develop analytical methods mainly on small molecules using equipment including HPLC, UHPLC, GC, and potentiometry. We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Requirements

• A Master’s degree or equivalent in Analytical Chemistry or related field with a minimum of 8 years, or a PhD with minimum of 5 years of experience in the pharmaceutical/biotech industry.
• Expertise in the operation of LC and GC
• Familiarity with the operation of potentiometry titrator, and TLC from multiple manufacturers
• Extensive experience in method development using HPLC/UPLC and GC
• Experience in analytical method validation
• Record of adhering to and promoting lab safety practices
• Good communications skills

Nice To Haves

• A PhD in Analytical Chemistry is preferred.
• In-depth understanding of the separation principles of LC, GC and method development software.
• Deep expertise in chromatography method development and trouble shoots
• Knowledge of QbD concepts, specification setting, and cGMP, with experience in contributing to regulatory submission
• Communicates effectively in individual and group settings and collaborate effectively in a multi-disciplinary team setting
• Demonstrated project management skills
• Consistent record of collaboration with scientists and other stakeholders at external enterprises
• Advanced scientific network in the industry and academia
• Record of patents and publications

Responsibilities

• Develop specific and robust analytical methods using equipment including HPLC, UHPLC, GC, and be responsible for validating the methods when necessary
• Analyze synthetic molecules mainly by HPLC/UHPLC, GC, potentiometry, and TLC.
• Perform quantification of impurities
• Perform mass balance studies
• Design and implement analytical strategies for synthesis intermediates and raw materials
• Develop effective collaborations with others within project teams and between analytical groups
• Generate technical reports independently
• Share knowledge and experience of analytical method development for synthetic molecules
• Introduce innovative analytical approaches to facilitate optimal decision-making.
• May serve as a project lead

Benefits

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Number of Employees: 5,001-10,000 employees