Associate Staff Scientist

University of Arkansas for Medical Sciences•Little Rock, AR

2d•Onsite

About The Position

POSITION SUMMARY The Winthrop P. Rockefeller Cancer Institute (WPRCI) at the University of Arkansas for Medical Sciences (UAMS) in Little Rock is seeking a manager for a newly founded Cryo-EM Facility. This facility will be equipped with a 200kV Glacios TEM, Falcon 4i direct electron detector, Selectris X Energy Filter, and auxiliary instrumentation for single particle sample preparation including vitrification devices (e.g., Vitrobot and Leica GP2). The successful candidate will be responsible for daily operations, cryo-EM sample vitrification, data collection and on-the-fly processing, and interaction with and training of users. Users will be from UAMS and institutions in Arkansas and the surrounding states. The University of Arkansas for Medical Sciences (UAMS) has a unique combination of education, research, and clinical programs that encourages and supports teamwork and diversity. We champion being a collaborative health care organization, focused on improving patient care and the lives of Arkansans. All UAMS employees will treat others with Dignity and Respect. We communicate and share complete and unbiased information, assuring our colleagues receive timely, complete, and accurate information in order to make informed decisions. We participate in institutional initiatives and encourage the participation of others. We collaborate in policy and program development, implementation, and evaluation using best practices in delivering quality service. All duties will be performed in accordance with the UAMS Core Concepts of Patient and Family Centered Care set forth by UAMS. These core concepts allow for an approach to health care that shapes policies, programs, facility design and staff day-to-day interactions. It leads to better health outcomes and wiser allocation of resources, and greater patient and family satisfaction. The core concepts of patient and family centered care consist of Dignity & Respect, Information Sharing, Participation, and Collaboration.

Requirements

PhD in physics, biophysics, or structural biology
Four (4+) years (Associate Scientist) or Seven (7+) years (Principal Scientist) of relevant experience including significant project management experience, personnel supervision and editorial and scientific contributions to grants.
Record of expertise in cryo-EM-based structural biology research founded on publications
Technical skills in cryo-EM sample vitrification, data acquisition, data processing and data analysis
Communication skills (oral and written)
Interpersonal skills to enable interacting and training others
Desire to make the cryo-EM Facility at UAMS a successful enterprise

Nice To Haves

Postdoctoral fellowship experience preferred.

Responsibilities

Management responsibilities for a multi-user research facility
Experience with cryo-TEM routine calibration and maintenance
Experience with routine maintenance of accessory equipment
Expertise with data collection and processing software for single particle analysis, including Cryosparc and Relion
Experience in training students and staff in all aspects of practical cryo-EM single particle analysis
Strong communication and organization skills to enable collaboration with faculty, students, staff, vendors, and service engineers
Keep accurate and clear records to help writing of manuscripts and center-related grant proposals as needed
Keep up with scientific literature relevant to new instrumentation, data processing, specimen preparation and imaging techniques.
Cryo-EM instruments management
Cryo-EM facility resource management
Vitrification
Data collection and processing
User training
May perform other duties as assigned.