Associate Staff Scientist (Ratner) Nerve Tumor Phenotypes

Cincinnati Children's•Cincinnati, OH

About The Position

There is an immediate opening for a motivated postdoctoral fellow to work in the laboratory of Dr. Nancy Ratner. We are looking for a PhD or MD/PhD to generate mouse models an cell lines that contain cells with Nf1 mutations plus variants in identified genes, to test if specific variants are modifiers of nerve tumor phenotypes. Strong candidates must be enthusiastic about working as part of a team of geneticists, statisticians, and rare disease experts to ensure variant selection and project completion. Expertise in molecular biology and neuroscience preferred.

Requirements

PhD
3+ years of work experience in a related job discipline
Expertise in molecular biology, protein chemistry and modern light microscopy is strongly preferred.

Nice To Haves

Expertise in molecular biology and neuroscience preferred.

Responsibilities

Conduct Research - Design, execute and record laboratory experiments; apply standard scientific/research protocols to experiments, research and improve current methods and evaluate innovative techniques.
Design and perform experiments and record data according to research protocol.
Independently reproduce, evaluate, research and improve techniques currently used.
Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition.
Maintain accurate and detailed records of all laboratory work and experiments.
Develop, set-up and verify new procedures in the laboratory.
Standardize and establish new published procedures; evaluate innovative techniques.
Develop new assays and new protocols; design formats.
Discuss relevant insights about experimental results with Director and provide useful recommendations and analysis.
Troubleshoot and correct erroneous results or problems with laboratory equipment.
Maintain and repair equipment; monitor proper use by personnel.
Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks.
Demonstrate performance at work, consistency in carrying out instructions, accuracy & attention to detail, achieving expected results & continuous improvement.
Draft, write and edit scientific reports, papers, journal articles and abstracts.
Present at local, national and international scientific meetings.
Train and supervise the work of other laboratory personnel as appropriate.
Maintain an integral role in the laboratory's meetings, presentations and publications.
Present information on research and laboratory work to others at laboratory meetings, journal clubs and seminars.
Demonstrate attendance and punctuality, ability to work independently & display initiative and dedication
Assist in preparing, writing and maintaining fiscal budget.
Monitor expenditures and prepare capital expenditure requests.
Prepare, approve and initiate check requests; track funding, maintain accurate balance and resolve any discrepancies.
May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction.
May provide input and feedback to managers on hiring decisions, professional development and performance management.