Associate Scientist

Singular Genomics • San Diego, CA

3d

About The Position

Singular Genomics is inventing at the forefront of genomics, one of the world’s fastest-growing industries. The commercially available G4® Sequencing Platform is a powerful, highly versatile benchtop genomic sequencer designed to produce fast and accurate results. In addition, the company is currently developing the G4X™ Spatial Sequencer, an upgrade to the G4, which will leverage Singular’s proprietary sequencing technology, applying it as an in situ readout for transcriptomics, proteomics and fluorescent H&E in tissue, with spatial context. Singular Genomics’ mission is to empower researchers and clinicians to advance science and medicine.
We foster a culture of creativity and technical excellence, both catalysts for innovation. We celebrate diversity, emphasize collaboration and, as we rapidly mature, we are constantly looking at ways we can do better for our people.
Our Headquarters are located on the Torrey Pines Mesa, in La Jolla, California at the center of the biotech hub. Our Manufacturing facility is in Sorrento Valley.
As an Associate Scientist working in the nucleotide chemistry group, you will be responsible for production of dye labeled NTPs, and other organic compounds, used in Singular’s NGS and Spatial technologies.

Requirements

• At least 5 years manufacturing organic compounds in a GMP environment
• Experience reverse phase, normal phase, and anion exchange chromatography
• Experience operating, maintaining, and troubleshooting HPLC instruments
• Experience operating, maintaining, and troubleshooting LC-MS instruments
• GDP, GLP, GMP experience
• Experience participating in ISO audits

Responsibilities

• Manufacture chemical compounds (nucleotides, linkers, triphosphates) using established synthesis schemes
• Document manufacture process on approved batch records, following good documentation practices
• Submit samples to internal and external QC departments
• Physically store inventory in lab at 4°C, -20°C, and -80°C storage conditions
• Work with manager and supply chain team to maintain adequate supply of raw materials
• Maintain laboratory instrumentation with the help of approved service contractors
• LC-MS
• HPLC (preparative and analytical)
• Rotary evaporators
• UV-Vis Spectrophotometers
• Work with facilities to address any safety issues in the lab

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: No Education Listed
• Number of Employees: 101-250 employees