Associate Scientist or Scientist, Immunology

Kymera Therapeutics • Watertown, MA

1d • $85,000 - $150,000

About The Position

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
How we work:
PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.
How you’ll make an impact:
Develop and optimize quantitative cell-based assays to facilitate SAR and MOA studies for novel degraders using both immortalized and primary cells.
Characterize lead molecules in vitro in human and animal primary immune and tissue cell types.
Communicate research findings in cross-functional project team meetings.
Review literature and conference proceedings to identify emerging technologies/assays and execute exploratory efforts for internal validation.
Maintain good written records of laboratory procedures, expand and maintain cell banks, and uphold high standards of lab citizenship among peers.

Requirements

• Relevant lab experience in immunology, cell biology, or related field.
• Extensive tissue culture experience with both immortalized and primary human cells.
• Deep knowledge in immunology, especially T-cell biology.
• Extensive hands-on experience with standard molecular and cell biology techniques: DNA construct design, transfection, viral transduction, genetic inhibition, ELISA, MSD, AlphaLISA, Western blot, RT-PCR, and flow cytometry, etc.
• Self-motivated, rigorous, efficient, and solution-oriented to deliver in a fast-paced environment with the ability to learn new areas as needed by project goals.
• Can independently develop/execute experiments and analyze/interpret results with minimal supervision while proactively seeking help and guidance as needed.
• Excellent organizational, verbal, and written communication skills and familiarity with electronic laboratory notebooks (ELN).

Responsibilities

• Develop and optimize quantitative cell-based assays to facilitate SAR and MOA studies for novel degraders using both immortalized and primary cells.
• Characterize lead molecules in vitro in human and animal primary immune and tissue cell types.
• Communicate research findings in cross-functional project team meetings.
• Review literature and conference proceedings to identify emerging technologies/assays and execute exploratory efforts for internal validation.
• Maintain good written records of laboratory procedures, expand and maintain cell banks, and uphold high standards of lab citizenship among peers.

Benefits

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $85,000 – $150,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: No Education Listed
• Number of Employees: 101-250 employees